Ivyspring期刊
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作者:Shuanglong Liu , Hongguang Liu , Gang Ren ...
来源:[J].Theranostics, 2011, Vol.1, pp.403-412Ivyspring
摘要:Purpose : Cystine knot (knottin) peptides, engineered to bind with high affinity to integrin receptors, have shown promise as molecular imaging agents in living subjects. The aim of the current study was to evaluate tumor uptake and in vivo biodistribution of 18F-label...
作者:Lihui Zou , Huiying Lai , Qi Zhou ...
来源:[J].Theranostics, 2011, Vol.1, pp.395-402Ivyspring
摘要:Vascular endothelial growth factor (VEGF), an important angiogenic factor that is able to stimulate the proliferation and migration of endothelial cells, is the best-studied hallmark of angiogenesis. Neovascularization is a major cause of age-related macular degeneration (AMD) wh...
作者:Manfred Wiessler , Ute Hennrich , Rüdiger Pipkorn ...
来源:[J].Theranostics, 2011, Vol.1, pp.381-394Ivyspring
摘要:Innovative and personalized therapeutic approaches result from the identification and control of individual aberrantly expressed genes at the transcriptional and post-transcriptional level. Therefore, it is of high interest to establish diagnostic, therapeutic and theranosti...
作者:Zibo Li , Qiaoling Jin , Chiunwei Huang ...
来源:[J].Theranostics, 2011, Vol.1, pp.371-380Ivyspring
摘要:The recent advancement of nanotechnology has provided unprecedented opportunities for the development of nanoparticle enabled technologies for detecting and treating cancer. Here, we reported the construction of a PET trackable organic nanoplatform based on phage particle fo...
作者:Jiyun Shi , Tracy W.B. Liu , Juan Chen ...
来源:[J].Theranostics, 2011, Vol.1, pp.363-370Ivyspring
摘要:Porphyrin based photosensitizers are useful agents for photodynamic therapy (PDT) and fluorescence imaging of cancer. Porphyrins are also excellent metal chelators forming highly stable metallo-complexes making them efficient delivery vehicles for radioisotopes. Here we inve...
作者:Tracy W.B. Liu , Juan Chen , Laura Burgess ...
来源:[J].Theranostics, 2011, Vol.1, pp.354-362Ivyspring
摘要:The complimentary ability of different noninvasive imaging technologies with therapeutic modalities can be used in tandem providing high-resolution and highly sensitive imaging of events at the molecular and cellular level providing a means for image-guided therapy. There is incr...
作者:Lixin Lang , Weihua Li , Hong-Mei Jia ...
来源:[J].Theranostics, 2011, Vol.1, pp.341-353Ivyspring
摘要:Direct bromination of the tyrosine residues of peptides and antibodies with bromine-76, to create probes for PET imaging, has been reported. For peptides that do not contain tyrosine residues, however, a prosthetic group is required to achieve labeling via conjugation to oth...
作者:Jiyun Shi , Yang Zhou , Sudipta Chakraborty ...
来源:[J].Theranostics, 2011, Vol.1, pp.322-340Ivyspring
摘要:Purpose: The purpose of this study was to demonstrate the valence of cyclic RGD peptides, P-RGD (PEG4-c(RGDfK): PEG4 = 15-amino-4,710,13-tetraoxapentadecanoic acid), P-RGD2 (PEG4-E[c(RGDfK)]2, 2P-RGD4 (E{PEG...
作者:Ashwinkumar A. Bhirde , Gang Liu , Albert Jin ...
来源:[J].Theranostics, 2011, Vol.1, pp.310-321Ivyspring
摘要:Recently portable Raman probes have emerged along with a variety of applications, including carbon nanotube (CNT) characterization. Aqueous dispersed CNTs have shown promise for biomedical applications such as drug/gene delivery vectors, photo-thermal therapy, and photoacoustic i...
作者:Fan Zhang , Lei Zhu , Gang Liu ...
来源:[J].Theranostics, 2011, Vol.1, pp.302-309Ivyspring
摘要:Purpose: Early assessment of tumor responses to chemotherapy could enhance treatment outcomes by ensuring that, from the beginning, treatments meet the individualized needs of patients. In this study, we applied multiple modality molecular imaging techniques to pre-clinical ...

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