PubMed期刊
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作者:Taunt Henry N , Stoffels Laura , Purton Saul
来源:[J].Bioengineered, 2018, Vol.9 (1), pp.48-54PubMed
摘要:Most commercial production of recombinant pharmaceutical proteins involves the use of mammalian cell lines, E. coli or yeast as the expression host. However, recent work has demonstrated the potential of eukaryotic microalgae as platforms for light-driven synthesis of such protei...
作者:Farakhor Sepideh , Shalchyan Vahid , Daliri Mohammad Reza
来源:[J].Bioengineered, 2019PubMed
摘要:Brain micro-electrical stimulation and its applications are among the most important issues in the field of brain science and neurophysiology. Deep brain stimulation techniques have been used in different theraputic or alternative medicine applications including chronic pain...
作者:Ma Jinfeng , Gao Weiliang , Gao Jisheng
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.229-239PubMed
摘要:Osteosarcoma (OS) is the most common primary malignant bone tumor. Secretory apolipoprotein J/clusterin (sCLU) is overexpressed in many cancers; however, its role in OS has not been previously investigated. The objectives of this study were to address this question and also ...
作者:Luo Jiaqi , Yang Lu , Long Zhen ...
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.162-171PubMed
摘要:Tonsillitis is the inflammation of the tonsils due to infection, many patients ultimately have to undergo tonsillectomy. In order to improve the accuracy of diagnosis and even create a new treatment for tonsillitis, we constructed a prokaryotic expression single-chain antibo...
作者:Liu Bing , Sun Xuerong
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.271-281PubMed
摘要:MicroRNA-25 (miR-25) has been reported to be overexpressed in numerous human tumors and plays a key role in tumor promotor. However, there are few reports about miR-25 expression and function in non-small cell lung cancer (NSCLC). In this study, we investigated the biological rol...
作者:Khajei Sina , Shalchyan Vahid , Daliri Mohammad Reza
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.250-260PubMed
摘要:Deep Brain Stimulation (DBS) is a medical-practical method and has been applied to solve many medical complications. Animal usage as sensors and actuators, mind-controlled machines, and animal navigation are some of the non-medical DBS applications. One of the brain areas used in...
作者:Cecil Alexander , Gentschev Ivaylo , Adelfinger Marion ...
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.190-196PubMed
摘要:Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a promising approach for cancer therapy. Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a therapeutic potential in treating human prostate and hepatocellular carcinomas in xenografted mice....
作者:Weng Jingyuan , Chen Liangliang , Cheng Yinchu ...
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.142-149PubMed
摘要:Quercetin-4'-O-glucoside is one of the major quercetin derivatives in the mature red onion bulb. It has an adjuvant effect on allergies, asthma, arthritis, and cancer. The present study aimed to use uridine diphosphate glycosyltransferase 88A1 (UGT88A1) from Arabidopsis thal...
作者:Gao Weiliang , Gao Jisheng , Chen Longying ...
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.261-270PubMed
摘要:The long noncoding RNA X-inactive specific transcript ( XIST ) plays vital roles in tumor progression. However, the underlying mechanisms remain unclear. This study investigated the effects and mechanisms of targeting XIST on osteosarcoma (OS) cells in vitro and in vivo . We used...
作者:Huang Jinjin , Wang Qing , Bu Wei ...
来源:[J].Bioengineered, 2019, Vol.10 (1), pp.150-161PubMed
摘要:We demonstrated previously that expression of Rhizomucor miehei lipase (RML) in Pichia pastoris could be significantly increased by addition of gene propeptide, optimized signal peptide codons and manipulation of gene dosage. In this study, effects of various strategies on the pr...

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