英国微生物学会
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作者:Maria Anele Romeo , Laura Masuelli , Aurelia Gaeta ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (1), pp.89-98英国微生物学会
摘要:Herpesviruses are known to manipulate autophagy to optimize their replication, counteract immune response and probably to promote tumourigenesis. This study explored, for the first time, the impact of human herpesvirus (HHV)-6 lytic infection on autophagy and demonstrated th...
作者:Kunal D. Pingale , Gayatri D. Kanade , Yogesh A. Karpe
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (3), pp.471-483英国微生物学会
摘要:Hepatitis E virus (HEV) induces interferons and regulates the induction of interferon-stimulated genes (ISGs) in the host cell. HEV infection has been shown to promote the expression of different ISGs, such as ISG15, IFIT1, MX1, RSAD2/Viperin and CxCL10, in cell culture and ...
作者:Oliver Schildgen , Sascha Gräper , Johannes Blümel ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (1), pp.105-117英国微生物学会
摘要:While it is fairly clear that herpes simplex virus (HSV) DNA replication requires at least seven virus-encoded proteins in concert with various host cell factors, the mode of this process in infected cells is still poorly understood. Using HSV-1 mutants bearing temperature-sensit...
作者:Paulo Vieira , Lev G. Nemchinov
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (4), pp.704-708英国微生物学会
摘要:The root lesion nematode Pratylenchus penetrans is a migratory species that attacks a broad range of plants. While analysing transcriptomic datasets of P. penetrans, we have identified a full-length genome of an unknown positive-sense single-stranded RNA virus, provisionally name...
作者:Anna Godi , Sara L. Bissett , Solène Masloh ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (2), pp.237-245英国微生物学会
摘要:We investigated the impact of naturally occurring variation within the major (L1) and minor (L2) capsid proteins on the antigenicity of human papillomavirus (HPV) type 52 (HPV52). L1L2 pseudoviruses (PsVs) representing HPV52 lineage and sublineage variants A1, A2, B1, B2, C ...
作者:Juliana Abreu Lima , Joaquim Pinto Nunes Neto , Karoline Silva Castro ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (2), pp.137-144英国微生物学会
摘要:Triniti virus (TNTV) has been isolated in Trinidad and Tobago and in Brazil. To date little is known about this virus, which is classified as an ungrouped virus within the family Togaviridae . Here, three isolates of TNTV were characterized both genetically and antigenically. The...
作者:Martina Gambato , Josep Gregori , Josep Quer ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (1), pp.63-68英国微生物学会
摘要:Cholestatic hepatitis C (CHC) is a severe form of hepatitis C virus (HCV) infection recurrence that leads to high graft loss rates early after liver transplantation (LT). To investigate the pathogenic mechanisms of CHC, we analysed HCV quasispecies in CHC patients compared to a c...
作者:Tsz On Lai , Siaw Shi Boon , Priscilla TY Law ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (3), pp.484-496英国微生物学会
摘要:Human papillomavirus (HPV) infection contributes to virtually all cases of cervical cancer, the fourth most common cancer affecting women worldwide. The oncogenicity of HPV is mainly attributable to the E6 and E7 oncoproteins. HPV-52 is the seventh most common HPV type globally, ...
作者:Emna Benzarti , Annick Linden , Daniel Desmecht ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (2), pp.119-132英国微生物学会
摘要:West Nile Virus, Usutu virus, Bagaza virus, Israel turkey encephalitis virus and Tembusu virus currently constitute the five flaviviruses transmitted by mosquito bites with a marked pathogenicity for birds. They have been identified as the causative agents of severe neurological ...
作者:Erica Martel , Emily Forzono , Richard Kurker ...
来源:[J].Journal of General Virology(IF 3.127), 2019, Vol.100 (3), pp.446-456英国微生物学会
摘要:The production of experimental molecular vaccines against foot-and-mouth disease virus utilizes the viral encoded 3C protease for processing of the P1 polyprotein. Expression of wild type 3C protease is detrimental to host cells. The molecular vaccine constructs containing t...

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