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作者:Juan Sebastian Yakisich , Rajkumar Venkatadri , Neelam Azad ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (8), pp.2033-2043Wiley
摘要:The efficacy of chemotherapy is hindered by both tumor heterogeneity and acquired or intrinsic multi‐drug resistance caused by the contribution of multidrug resistance proteins and stemness‐associated prosurvival markers. Therefore, targeting multi‐drug resistant cells ...
作者:Asish K. Ghosh , Rahul Rai , Panagiotis Flevaris ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (8), pp.1941-1956Wiley
摘要:Epigenetic changes play a pivotal role in the development of a wide spectrum of human diseases including cardiovascular diseases, cancer, diabetes, and intellectual disabilities. Cardiac fibrogenesis is a common pathophysiological process seen during chronic and stress‐induc...
作者:Jyotirmaya Behera , Jyoti Bala , Mohammed Nuru ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (10), pp.2704-2709Wiley
摘要:In the last few decades, perturbation in methyl‐group and homocysteine (Hcy) balance have emerged as independent risk factors in a number of pathological conditions including neurodegenerative disease, cardiovascular dysfunction, cancer development, autoimmune disease, and k...
作者:Agnieszka Piwkowska
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (4), pp.691-697Wiley
摘要:Podocytes and their foot processes form an important cellular layer of the glomerular barrier involved in the regulation of glomerular permeability. Disturbing the function of podocytes plays a central role in the development of proteinuria in diabetic nephropathy. Retractio...
作者:Rabia Islam , Won‐Joon Yoon , Hyun‐Mo Ryoo
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (9), pp.2339-2347Wiley
摘要:Pin1 is an enzyme that specifically recognizes the peptide bond between phosphorylated serine or threonine (pS/pT‐P) and proline. This recognition causes a conformational change of its substrate, which further regulates downstream signaling. Pin1−/− mice show...
作者:Sadaf Riaz Pharm.D, MSc , Asad Zeidan PhD , Fatima Mraiche PhD
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (12), pp.3244-3250Wiley
摘要:Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need to further investigate the signaling pathways that mediate ...
作者:Erik H. Koritzinsky , Jonathan M. Street , Robert A. Star ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (7), pp.1587-1590Wiley
摘要:Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology. We suggest ...

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