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作者:Ryoichi Tomiyama , Ken Takakura , Shouhei Takatou ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:3,4‐dihydroxybenzalacetone (DBL) and Caffeic acid phenethyl ester (CAPE) are both catechol‐containing phenylpropanoid derivatives with diverse bioactivities. In the present study, we analyzed the ability of these compounds to activate the unfolded protein response (UPR) and ...
作者:Amirhossein Sahebkar , Elena Sancho , David Abelló ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Currently, a liver biopsy remains the only reliable way to precisely diagnose non‐alcoholic fatty liver disease (NAFLD) and establish the severity of liver injury, presence of fibrosis, and architecture remodeling. However, the cost and the intrinsic invasive procedure of a ...
作者:Elena R. Andreeva , Olga O. Udartseva , Olga V. Zhidkova ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Multipotent mesenchymal stromal cells (MSCs) are considered cue regulators of tissue remodeling. Their activity is strongly governed by local milieu, where O2 level is most important. The elevation of inflammatory mediators and acute O2 lowering may add...
作者:Pascale Gerbaud , Jean Guibourdenche , Rafika Jarray ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Psoriasis vulgaris is a common skin inflammatory disease characterized by recurrent flare episodes associated with scaly well‐demarcated skin plaques. Skin biopsies from psoriatic patients with high PASI score (22.67 ± 8.67) and from HD were used to study APN/CD13. APN/CD13 ...
作者:Joao Costa‐Rodrigues , Isabel Rocha , Maria H. Fernandes
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Cigarette smoke is associated to pathological weakening of bone tissue, being considered an important playmaker in conditions such as osteoporosis and periodontal bone loss. In addition, it is also associated with an increased risk of failure in bone regeneration strategies....
作者:Vincent J. Tocco , Yuan Li , Keith G. Christopher ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Actomyosin stress fibers impinge on the nucleus and can exert compressive forces on it. These compressive forces have been proposed to elongate nuclei in fibroblasts, and lead to abnormally shaped nuclei in cancer cells. In these models, the elongated or flattened nuclear sh...
作者:Jiaqi Liu , Ziye Xu , Weiche Wu ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:The cyclic adenosine monophosphate (cAMP)—protein kinase A (PKA) signaling pathway plays important role in regulating energy homeostasis. Many of the effects of the cAMP‐PKA signaling is mediated through the cAMP responsive element binding protein (CREB) and its coactivator ...
作者:Elham Abdollahi , Amir Abbas Momtazi , Thomas P. Johnston ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities. Novel animal and human studies indicate that curcumin can affect different immune cells, such as various T lymphocyte subsets, macrophages, dendritic cells, B lymphocytes and natural kil...
作者:Andrew J. Fritz , Prachi N. Ghule , Joseph R. Boyd ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Alterations in nuclear morphology are common in cancer progression. However, the degree to which gross morphological abnormalities translate into compromised higher‐order chromatin organization is poorly understood. To explore the functional links between gene expression and...
作者:Balasubramanian Arumugam , Mariappanadar Vairamani , Nicola C. Partridge ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2)Wiley
摘要:Transforming growth factor‐beta1 (TGF‐β1), a highly abundant growth factor in skeletal tissues, stimulates matrix metalloproteinase‐13 (MMP‐13) expression in osteoblastic cells. MMP‐13 plays a critical role in bone remodeling. Runx2, a bone transcription factor, is...

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