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来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (1), pp.1-3
作者:Helen Vaher , Anet Kivihall , Toomas Runnel ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (1), pp.51-60
摘要:Abstract(#br)Psoriasis is a chronic inflammatory skin disease with numerous involved factors. miR‐146a and miR‐146b (miR‐146a/b) are anti‐inflammatory miRNAs that are increased in psoriatic skin. SERPINB2 has been shown to be upregulated in the inflammation and infectio...
作者:Vivian Lee , Michael D. Gober , Hasan Bashir ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (1), pp.29-38
摘要:Abstract(#br)Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer and is associated with cumulative UV exposure. Studies have shown that prolonged voriconazole use promotes cSCC formation; however, the biological mechanisms responsible for t...
作者:Borbála Kiss , Magdolna Szántó , Csaba Hegedűs ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (1), pp.79-85
摘要:Abstract(#br)Poly(ADP‐ribose) polymerase‐1 (PARP1) is a pro‐inflammatory protein, whose pro‐inflammatory properties were demonstrated in human. The pro‐inflammatory properties of PARP1 were shown in Th1‐ and Th2‐mediated inflammatory pathologies, but not Th17‐...
作者:Xingqi Zhang , Kevin J. McElwee
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (3), pp.239-242
摘要:Abstract(#br)In this commentary, we focus on allergy as a facilitating factor in the pathogenesis of alopecia areata (AA). From previous studies on AA, it is well known that subsets of patients can have one or more of; seasonal relapse, comorbid atopic rhinitis, asthma and dermat...
作者:Jinpeng Lv , Ying Fu , Yan Cao ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (2), pp.149-157
摘要:Abstract(#br)Isoliquiritigenin (ISL), a flavonoid component from the hydrolysis products of licorice root. It has been reported that ISL inhibited melanogenesis by suppressing the tyrosinase activity in human melanocytes. Recently, ISL was found to induce melanin degradation...
作者:Isabella Doche , George L. Wilcox , Marna Ericson ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (3), pp.282-285
摘要:Abstract(#br)Lichen planopilaris ( LPP ) and frontal fibrosing alopecia ( FFA ) are lymphocytic scarring alopecias affecting primarily the scalp. Although both diseases may share some clinical and histopathological features, in the last decade, FFA has become an “epidemic” p...
作者:Hoon Kang , Wen‐Yu Wu , Mei Yu ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (3), pp.254-258
摘要:Abstract(#br)Alopecia areata (AA) is thought to be an autoimmune process. In other autoimmune diseases, the innate immune system and Toll‐like receptors (TLRs) can play a significant role. Expression of TLR7, TLR9 and associated inducible genes was evaluated by quantitative ...
作者:Adrian Cuellar‐Barboza , Jesus Alberto Cardenas‐de la Garza , Luis Gerardo Cruz‐Gómez ...
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (3), pp.259-264
摘要:Abstract(#br)Alopecia areata (AA) is an autoimmune disease of the hair follicle. Keratinocytes of the hair follicle generate an immunosuppressive environment by the local secretion of hormones of the hypothalamic‐pituitary‐adrenal axis of the skin (skin HPA analog). Our obje...
作者:David Grand , Kristina Navrazhina , John W. Frew
来源:[J].Experimental Dermatology(IF 3.578), 2020, Vol.29 (1), pp.86-92
摘要:Abstract(#br)Complement inhibition has been identified as a potential therapeutic target for multiple inflammatory disorders including Hidradenitis Suppurativa (HS). It is currently unclear how complement integrates into our current model of molecular pathogenesis in HS and ...

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