Elsevier期刊
期刊
会议
图书
作者:Sneha Ranade , Amrita Bajaj , Vaishali Londhe ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017Elsevier
摘要:Abstract(#br)Topical film-forming metered dose spray formulations were designed for management of pain. Ropivacaine, a local anesthetic is explored for its topical efficacy in alleviating pain. Metered dose spray containers, organic solvents, film forming polymers and permeation ...
作者:Masakazu Fukuda , Atsushi Watanabe , Akira Hayasaka ...
来源:[J].European Journal of Pharmaceutics and Biopharmaceutics(IF 3.826), 2017, Vol.112, pp.132-137Elsevier
摘要:Abstract(#br)In this study, we investigated the concentration range in which self-association starts to form in humanized IgG monoclonal antibody (mAb) solutions. Furthermore, on the basis of the results, we developed a practical method of screening for low-viscosity antibod...
作者:Domenico Iacopetta , Camillo Rosano , Francesco Puoci ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017, Vol.96, pp.263-272Elsevier
摘要:Abstract(#br)Natural or synthetic carbazole derivatives have recently attracted the attention of the scientific world because of their multiple biological activity, leading to an increase of designed, synthesized and studied analogues. In this paper, four 1,4-dimethylcarbazole de...
作者:Sophia Malli , Christian Bories , Bénédicte Pradines ...
来源:[J].European Journal of Pharmaceutics and Biopharmaceutics(IF 3.826), 2017, Vol.112, pp.143-147Elsevier
摘要:Abstract(#br)The objective of this work is to design topically-applied thermosensitive and mucoadhesive hydrogel containing metronidazole (MTZ) for the treatment of Trichomonas vaginalis infections. Hydrogel composed of pluronic® F127 (20 wt%), chitosan (1 wt%) and metronida...
作者:Joana Sousa , Gilberto Alves , Paula Oliveira ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017, Vol.97, pp.30-37Elsevier
摘要:Abstract(#br)Intranasal administration of antibiotics is an alternative and attractive delivery approach in the treatment of local infections such as chronic rhinosinusitis. This topical route has the advantage of delivering high drug concentrations directly to the site of infect...
作者:Stavroula Nanaki , Panoraia I. Siafaka , Dorothea Zachariadou ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017, Vol.99, pp.32-44Elsevier
摘要:Abstract(#br)In this work, high surface area mesoporous silica (SBA-15) was loaded with paclitaxel (taxol, PTX) and was further entrapped into poly(lactic acid- co -glycolic acid) (PLGA) microparticles (MPs). A modified solvent evaporation-emulsion method was used in order t...
作者:Harsh Vardhan , Pooja Mittal , Sandeep Kumar Reddy Adena ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017, Vol.99, pp.85-94Elsevier
摘要:Abstract(#br)In the present research an attempt was made to develop and optimize docetaxel-loaded polyhydroxybutyrate- co -hydroxyvalerate (PHBV) nanoparticles, using modified emulsification solvent evaporation technique and design of experiment (DOE) methodology. Formulatio...
作者:Hiroki Suzuki , Kodai Ueno , Takahiro Mizumoto ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017, Vol.96, pp.107-114Elsevier
摘要:Abstract(#br)The present study aimed to develop an inhalable self-micellizing solid dispersion of cyclosporine A (SMSD/CsA) for the direct delivery to the respiratory system with improved therapeutic efficacy and minimized systemic exposure. SMSD/CsA was obtained by wet-mill...
作者:Justine Thiry , Fabrice Krier , Shenelka Ratwatte ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2017, Vol.96, pp.590-597Elsevier
摘要:Abstract(#br)The aim of this study was to evaluate hot-melt extrusion (HME) as a continuous process to form cyclodextrin (CD) inclusion complexes in order to increase the solubility and dissolution rate of itraconazole (ITZ), a class II model drug molecule of the Biopharmace...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×