European Cells and Materials (eCM)
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作者:I A Otto , R Levato , W R Webb ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.132-150European Cells and Materials (eCM)
摘要:Paramount for the generation of auricular structures of clinically-relevant size is the acquisition of a large number of cells maintaining an elastic cartilage phenotype, which is the key in producing a tissue capable of withstanding forces subjected to the auricle. Current ...
作者:R Bell , M A Robles-Harris , M Anderson ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.44-56European Cells and Materials (eCM)
摘要:Tendinopathy is a common and progressive musculoskeletal disease. Increased apoptosis is an end-stage tendinopathy manifestation, but its contribution to the pathology of the disease is unknown. A previously established in vivo model of fatigue damage accumulation shows that incr...
作者:D M Varma , H A Lin , R G Long ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.300-317European Cells and Materials (eCM)
摘要:Back and neck pain are commonly associated with intervertebral disc (IVD) degeneration. Structural augmentation of diseased nucleus pulposus (NP) tissue with biomaterials could restore degeneration-related IVD height loss and degraded biomechanical behaviors; however, effective N...
作者:C S Chang , C Y Yang , H Y Hsiao ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.350-364European Cells and Materials (eCM)
摘要:Tissue engineering has the potential to overcome the limitations of tracheal reconstruction. To tissue-engineer a tracheal cartilage, auricular chondrocytes were encapsulated in a photocurable poly(ethylene glycol)/poly(ε-caprolactone) (PEG/PCL) hydrogel. Chondrogenic genes,...
作者:P P Balraadjsing , E C de Jong , D W Grijpma ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.103-116European Cells and Materials (eCM)
摘要:Biomaterial-associated infections (BAIs) are frequent complications in the use of medical devices (biomaterials) correlated with considerable patient discomfort and high treatment costs. The presence of a biomaterial in the host causes derangement of local immune responses i...
作者:M M Gao , Q N Su , T Z Liang ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.1-14European Cells and Materials (eCM)
摘要:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is the main source of extracellular pyrophosphate. Along with tissue-nonspecific alkaline phosphatase (TNAP), ENPP1 plays an important role in balancing bone mineralisation. Although well established in pre-osteoblasts, t...
作者:S M Shiels , M Bouchard , H Wang ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.178-194European Cells and Materials (eCM)
摘要:BThe use of internal intramedullary nails for long bone fracture fixation is a common practice among surgeons. Bacteria naturally attach to these devices, increasing the risk for wound infection, which can result in non- or malunion, additional surgical procedures and extended ho...
作者:A Feldmann , P Wili , G Maquer ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.25-33European Cells and Materials (eCM)
摘要:Surgical interventions close to vulnerable structures, such as nerves, require precise handling of surgical instruments and tools. These tools not only pose the risk of mechanical damage to soft tissues, but they also generate heat, which can lead to thermal necrosis of bone...
作者:M Majewski , P Heisterbach , C Jaquiéry ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.318-334European Cells and Materials (eCM)
摘要:Several growth factors (GFs) are expressed as tendons heal, but it remains unknown whether their combined application enhances the healing process. This matter was addressed by applying a combination of basic fibroblast growth factor (bFGF), bone morphogenetic protein 12 (BM...
作者:J Melke , F Zhao , B van Rietbergen ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.57-68European Cells and Materials (eCM)
摘要:Spinner flask bioreactors have often been employed for bone tissue engineering. However, the reasons for their success in facilitating bone growth remain inconclusive. It was hypothesised that engineered bone tissue formation can be attributed to mechanical stimuli, which ca...

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