Elsevier期刊
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作者:Ryo Nakabayashi , Kazuki Saito
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.8-16Elsevier
摘要:The advent of the genome-editing era greatly increases the opportunities for synthetic biology research that aims to enhance production of potentially useful bioactive metabolites in heterologous hosts. A wide variety of sulfur (S)-containing metabolites (S-metabolites) are known...
作者:Allison M Roberts , Carl C Ward , Daniel K Nomura
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.25-33Elsevier
摘要:Despite the completion of human genome sequencing efforts nearly 15 years ago that brought with it the promise of genome-based discoveries that would cure human diseases, most protein targets that control human diseases have remained largely untranslated, in-part because the...
作者:Vladimir Sarpe , David C Schriemer
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.110-117Elsevier
摘要:Large and disparate sets of LC–MS data are generated by modern metabolomics profiling initiatives, and while useful software tools are available to annotate and quantify compounds, the field requires continued software development in order to sustain methodological innovatio...
作者:Joana Díaz-Gómez , Richard M Twyman , Changfu Zhu ...
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.44, pp.115-123Elsevier
摘要:Biofortification is an effective and economical method to improve the micronutrient content of crops, particularly staples that sustain human populations in developing countries. Whereas conventional fortification requires artificial additives, biofortification involves the synth...
作者:Jennifer Haggarty , Karl EV Burgess
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.77-85Elsevier
摘要:The metabolome is the complete complement of metabolites (small organic biomolecules). In order to comprehensively understand the effect of stimuli on a biological system, it is important to detect as many of the metabolites within that system as possible. This review briefly des...
作者:Stéphanie Heux , Cécilia Bergès , Pierre Millard ...
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.104-109Elsevier
摘要:The rise of high throughput (HT) strain engineering tools accompanying the area of synthetic biology is supporting the generation of a large number of microbial cell factories. A current bottleneck in process development is our limited capacity to rapidly analyze the metabolic st...
作者:Michelle K McGuire , Mark A McGuire
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.44, pp.63-68Elsevier
摘要:Contrary to long-held dogma, human milk is not sterile. Instead, it provides infants a rich source of diverse bacteria, particularly microbes belonging to the Staphylococcus , Streptococcus , and Pseudomonas genera. Very little is known about factors that influence variation...
作者:Wei Zhang , Thomas Hankemeier , Rawi Ramautar
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.1-7Elsevier
摘要:Capillary electrophoresis–mass spectrometry has shown considerable potential for profiling polar ionogenic compounds in metabolomics. Hyphenation of capillary electrophoresis to mass spectrometry is generally performed via a sheath–liquid interface. However, the electrophore...
作者:Julia I Martien , Daniel Amador-Noguez
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.43, pp.118-126Elsevier
摘要:Biofuel production from plant biomass is a promising source of renewable energy [1]. However, efficient biofuel production involves the complex task of engineering high-performance microorganisms, which requires detailed knowledge of metabolic function and regulation. This review...
作者:Balaji Srinivasan , Seoho Lee , David Erickson ...
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2017, Vol.44, pp.103-108Elsevier
摘要:Precision nutrition encompasses prevention and treatment strategies for optimizing health that consider individual variability in diet, lifestyle, environment and genes by accurately determining an individual's nutritional status. This is particularly important as malnutrition no...

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