作者:Michael M Barrus , Catharine A Winstanley
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.99-105Elsevier
摘要:Impulsivity is thought to contribute to the development and maintenance of gambling disorder, but the mechanistic relationship between these complex and multifaceted behaviors is unclear. Animal models have been developed to examine various aspects of each, and have provided insi...
作者:Oliver T Wolf
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.14, pp.40-46Elsevier
摘要:Stress impairs memory retrieval. Recent findings illustrate the temporal dynamics and the underlying mechanisms of this effect. The effect appears to occur in multiple memory systems, ranging from striatal-based stimulus-response memory to prefrontal-based extinction memory. The ...
作者:Andreas Büttner
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.8-12Elsevier
摘要:The predominantly abused illicit substances include cannabis, opiates, cocaine, amphetamine, methamphetamine and their derivatives. Recently, the abuse of new psychoactive substances has become an increasing problem. In human drug abusers a broad spectrum of changes affecting the...
作者:Victoria Manning , Antonio Verdejo-Garcia , Dan I Lubman
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.40-45Elsevier
摘要:There is consistent evidence of impairments in cognitive functioning, as well as structural and neural processing abnormalities among substance-dependent populations. In this review, we summarise recent neurocognitive and neuroimaging research, particularly focussing on studies t...
作者:George H Vousden , Amy L Milton
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.158-163Elsevier
摘要:Memory reconsolidation — the process by which memories can become destabilised at retrieval, and be updated or modified — offers a potential therapeutic opportunity for mental health disorders based upon maladaptive emotional memories, such as drug addiction. Blocking the re...
作者:Karl Ebner , Nicolas Singewald
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.14, pp.54-64Elsevier
摘要:Many individuals experience stressful life events, but only a minority develops stress-related pathologies including mental disorders such as depression or anxiety disorders. Such individual differences in stress vulnerability are based on alterations in neural circuits/mechanism...
作者:Louk JMJ Vanderschuren , A Maryse Minnaard , Johanna AS Smeets ...
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.77-84Elsevier
摘要:Substance addiction is a chronic relapsing brain disorder, characterized by loss of control over substance use. In recent years, there has been a lively interest in animal models of loss of control over substance use, using punishment paradigms. We provide an overview of punishme...
作者:Marco Leyton
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.130-138Elsevier
摘要:Is altered dopamine transmission a pre-existing vulnerability trait for addiction? Preliminary support for this hypothesis has been provided by recent neuroimaging studies. While most effects remain to be replicated, there is now evidence that, compared to healthy controls, peopl...
作者:Maxime Fouyssac , Barry J Everitt , David Belin
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.144-151Elsevier
摘要:Over the course of addiction drug seeking, initially volitional, progressively becomes habitual and then compulsive. These psychological transitions in the control over behaviour are underlined by functional intrastriatal shifts from the nucleus accumbens to the dorsolateral stri...
作者:Adrianna Mendrek , Liana Fattore
来源:[J].Current Opinion in Behavioral Sciences, 2017, Vol.13, pp.152-157Elsevier
摘要:Men and women affected by schizophrenia display different age of onset, symptom profile and course of the disease. Similarly, men and women differ in the prevalence and frequency of drug use, pattern and reasons of use, and vulnerability to develop drug addiction. An underst...


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