PubMed期刊
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作者:Wu Z-Y , Xu T-L
来源:[J].Amino acids(IF 3.914), 2003, Vol.24 (1-2), pp.155-61PubMed
摘要:Taurine is one of the most abundant free amino acids in the immature mammalian central nervous system. In the present study, whole-cell patch-clamp recordings were made to examine taurine-evoked currents ( I(Tau)) in acutely dissociated immature rat hippocampal CA1 neurons. Tauri...
作者:Farias Ana Paula S F , Carneiro Cristine E A , de Batista Fonseca Inês C ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1401-12PubMed
摘要:Few prebiotic chemistry experiments have assessed the adsorption of biomolecules by iron oxide-hydroxides. The present work investigated the effects of cations in artificial seawaters on the adsorption of Gly, α-Ala and β-Ala onto goethite, and vice versa. Goethite served to...
作者:Freidel Christoph , Kaloyanova Stefka , Peneva Kalina
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1357-72PubMed
摘要:This review focuses on the various approaches to covalently attach a chromophore to a biomolecule of interest in site-specific manner. Novel methods like inverse electron-demand Diels-Alder reaction, Pictet-Spengler ligation and enzyme tags like SNAP and Halo-tags are critically ...
作者:Royes Luiz Fernando Freire , Gabbi Patrícia , Ribeiro Leandro Rodrigo ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1373-89PubMed
摘要:Hyperammonemia is a common finding in children with methylmalonic acidemia. However, its contribution to methylmalonate-induced excitotoxicty is poorly understood. The aim of this study was to evaluate the mechanisms by which ammonia influences in the neurotoxicity induced b...
作者:Ulivelli Monica , Priora Raffaella , Di Giuseppe Danila ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1477-89PubMed
摘要:The toxicity risk of hyperhomocysteinemia is prevented through thiol drug administration which reduces plasma total homocysteine (tHcy) concentrations by activating thiol exchange reactions. Assuming that cysteine (Cys) is a homocysteinemia regulator, the hypothesis was verified ...
作者:Li Ruiting , Liu Peifang , Liu Peijia ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1523-32PubMed
摘要:Branched-chain amino acids (BCAAs) and branched-chain α-keto acids (BCKAs) play significant biological roles as they are involved in protein and neurotransmitter synthesis as well as energy metabolism pathways. To routinely and accurately study the dynamics of BCAAs and BCKA...

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