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作者:Farias Ana Paula S F , Carneiro Cristine E A , de Batista Fonseca Inês C ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1401-12PubMed
摘要:Few prebiotic chemistry experiments have assessed the adsorption of biomolecules by iron oxide-hydroxides. The present work investigated the effects of cations in artificial seawaters on the adsorption of Gly, α-Ala and β-Ala onto goethite, and vice versa. Goethite served to...
作者:Freidel Christoph , Kaloyanova Stefka , Peneva Kalina
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1357-72PubMed
摘要:This review focuses on the various approaches to covalently attach a chromophore to a biomolecule of interest in site-specific manner. Novel methods like inverse electron-demand Diels-Alder reaction, Pictet-Spengler ligation and enzyme tags like SNAP and Halo-tags are critically ...
作者:Royes Luiz Fernando Freire , Gabbi Patrícia , Ribeiro Leandro Rodrigo ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1373-89PubMed
摘要:Hyperammonemia is a common finding in children with methylmalonic acidemia. However, its contribution to methylmalonate-induced excitotoxicty is poorly understood. The aim of this study was to evaluate the mechanisms by which ammonia influences in the neurotoxicity induced b...
作者:Ulivelli Monica , Priora Raffaella , Di Giuseppe Danila ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1477-89PubMed
摘要:The toxicity risk of hyperhomocysteinemia is prevented through thiol drug administration which reduces plasma total homocysteine (tHcy) concentrations by activating thiol exchange reactions. Assuming that cysteine (Cys) is a homocysteinemia regulator, the hypothesis was verified ...
作者:Li Ruiting , Liu Peifang , Liu Peijia ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1523-32PubMed
摘要:Branched-chain amino acids (BCAAs) and branched-chain α-keto acids (BCKAs) play significant biological roles as they are involved in protein and neurotransmitter synthesis as well as energy metabolism pathways. To routinely and accurately study the dynamics of BCAAs and BCKA...
作者:Bodnar Magdalena , Luczak Magdalena , Bednarek Kinga ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1469-76PubMed
摘要:Relapse and metastasis are the main causes of unfavorable outcome in head and neck cancers. Whereas, understanding of the molecular background of these processes is far from being complete. Therefore, in this study we aimed to identify potential biomarker candidates of relapse an...
作者:Zhang Yi-Le , Han Zhao-Feng , Sun Ying-Pu
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1509-21PubMed
摘要:The recognition and association between Ca(2+)/calmodulin-activated protein kinase II-α (CaMKIIα) and multi-PDZ domain protein 1 (MUPP1) plays an important role in sperm acrosome reaction and human fertilization, which is mediated by the binding of CaMKIIα's C-terminal tail ...
作者:Hirsh Layla , Piovesan Damiano , Paladin Lisanna ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1391-400PubMed
摘要:Over the last decade, numerous studies have demonstrated the fundamental importance of tandem repeat (TR) proteins in many biological processes. A plethora of new repeat structures have also been solved. The recently published RepeatsDB provides information on TR proteins. Howeve...
作者:Zanin Luciana Puia Moro , de Araujo Alexandre Suman , Juliano Maria Aparecida ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1433-44PubMed
摘要:We investigate the effect of the N-terminus modification of the L1A, a synthetic octadecapeptide, on its helical content, affinity and lytic action in model membranes and on its hemolytic and antibacterial activities. L1A and its acetylated analog displayed a selective antibacter...
作者:Teloh Johanna K , Dohle Daniel-Sebastian , Petersen Miriam ...
来源:[J].Amino acids, 2016, Vol.48 (6), pp.1423-32PubMed
摘要:Bretschneider (histidine-tryptophan-ketoglutarate, HTK) solution employed for induction of cardioplegic arrest possesses a high histidine concentration (198 mM). Due to the large volume administered, massive amounts of histidine are incorporated. The aim of the study was to ...

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