国际光学工程学会
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作者:Yong Zhou , Alejandro Garcia-Uribe ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041003-041003SPIE
摘要:While lasers have been commonly used as illumination sources in photoacoustic (PA) imaging, their high purchase and maintenance costs, as well as their bulkiness, have hindered the rapid clinical dissemination of PA imaging. With this in mind, we explore an alternative illum...
作者:Yong Zhou , Ruiying Zhang ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041004-041004SPIE
摘要:Circulating tumor cell (CTC) clusters, arising from multicellular groupings in a primary tumor, greatly elevate the metastatic potential of cancer compared with single CTCs. High-throughput detection and quantification of CTC clusters are important for understanding the tumor met...
作者:Yong Zhou , Joemini Poudel ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2015, Vol.20 (8), pp.087001-087001SPIE
摘要:We propose a saline injection-based method to quantify blood flow velocity in vivo with acoustic-resolution photoacoustic tomography. By monitoring the saline–blood interface propagating in the blood vessel, the flow velocity can be resolved. We first demonstrated our method...
作者:Yong Zhou , Junjie Yao ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (3), pp.037001-037001SPIE
摘要:Currently, laser fluence calibration is typically required for quantitative measurement of particle concentration in photoacoustic imaging. Here, we present a calibration-free method to quantify the absolute particle concentration by statistically analyzing photoacoustic signals....
作者:Yong Zhou , Junjie Yao , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (6), pp.061007-061007SPIE
摘要:Photoacoustic tomography (PAT) has become one of the fastest growing fields in biomedical optics. Unlike pure optical imaging, such as confocal microscopy and two-photon microscopy, PAT employs acoustic detection to image optical absorption contrast with high-resolution deep...
作者:Yong Zhou , Jinyang Liang ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2015, Vol.20 (12), pp.126008-126008SPIE
摘要:Characterization of blood vessel elastic properties can help in detecting thrombosis and preventing life-threatening conditions such as acute myocardial infarction or stroke. Vascular elastic photoacoustic tomography (VE-PAT) is proposed to measure blood vessel compliance in...
作者:... Rui Yao , Qiang Niu , Yong Zhou
来源:[J].Journal of Electronic Imaging(IF 1.061), 2015, Vol.24 (6), pp.063023-063023SPIE
摘要:Concatenating multicamera videos with differing centers of projection into a single panoramic video is a critical technology of many important applications. We propose a real-time video fusion approach to create wide field-of-view video. To provide a fast and accurate video regis...
作者:Yong Zhou , Song Hu ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (2), pp.020501-020501SPIE
摘要:Angiogenesis in a tumor region creates arteriovenous (AV) shunts that cause an abnormal venous blood oxygen saturation ( sO 2 ) distribution. Here, we applied optical-resolution photoacoustic microscopy to study the AV shunting in vivo . First, we built a phantom to image sO 2 di...
作者:Yong Zhou , Lei Gong
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (6), pp.066011-066011SPIE
摘要:We report quantitative photoacoustic elastography (QPAE) capable of measuring Young’s modulus of biological tissue in vivo in humans. By combining conventional PAE with a stress sensor having known stress–strain behavior, QPAE can simultaneously measure strain and stress, fr...
作者:... Pengfei Hai , Yong Zhou , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (6), pp.066005-066005SPIE
摘要:Grueneisen relaxation photoacoustic microscopy (GR-PAM) can achieve optically defined axial resolution, but it has been limited to ex vivo demonstrations so far. Here, we present the first in vivo image of a mouse brain acquired with GR-PAM. To induce the GR effect, an inten...

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