PubMed期刊
期刊
会议
图书
作者:Yang Hongyu , Khan Awais ...
来源:[J].BMC genetics(IF 2.808), 2017, Vol.18 (1), pp.41PubMed
摘要:The SnRKs (sucrose non-fermenting 1 related protein kinase) are a gene family coding for Ser/Thr protein kinases and play important roles in linking the tolerance and metabolic responses of plants to abiotic stresses. To date, no genome-wide characterization of the sucrose non-fe...
作者:Yang Hongyu , Rao Yuefeng ...
来源:[J].The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale(IF 1.02), 2016, Vol.2016, pp.9032809PubMed
摘要:Epilepsy is one of the most widespread serious neurological disorders, and an aetiological explanation has not been fully identified. In recent decades, a growing body of evidence has highlighted the influential role of autoimmune mechanisms in the progression of epilepsy. The hy...
作者:Yang Hongyu , Mo Jun ...
来源:[J].PeerJ, 2018, Vol.6, pp.e4206PubMed
摘要:Targeting tyrosinase is considered to be an effective way to control the production of melanin. Tyrosinase inhibitor is anticipated to provide new therapy to prevent skin pigmentation, melanoma and neurodegenerative diseases. Herein, we report our results in identifying new ...
作者:Yang Hongyu , Khalsa Dharma S
来源:[J].International psychogeriatrics, 2017, Vol.29 (4), pp.557-567PubMed
摘要:Global population aging will result in increasing rates of cognitive decline and dementia. Thus, effective, low-cost, and low side-effect interventions for the treatment and prevention of cognitive decline are urgently needed. Our study is the first to investigate the effect...
作者:Yang Hongyu , Zhu Qiang ...
来源:[J].World journal of microbiology & biotechnology, 2016, Vol.32 (11), pp.176PubMed
摘要:Prolyl aminopeptidases are specific exopeptidases that catalyze the hydrolysis of the N-terminus proline residue of peptides and proteins. In the present study, the prolyl aminopeptidase gene (pap) from Aspergillus oryzae JN-412 was optimized through the codon usage of Pichi...
作者:Yang Hongyu , Zhang Chao ...
来源:[J].Epilepsy & behavior : E&B, 2018, Vol.81, pp.41-48PubMed
摘要:The aims of this study were to investigate the brain network alternation in patients with temporal lobe epilepsy (TLE) with and without cognitive impairment (CI) using functional magnetic resonance imaging (fMRI) and to further explore the potential mechanisms of epilepsy-induced...
作者:Yang Hongyu , Siddarth Prabha ...
来源:[J].Journal of Alzheimer's disease : JAD, 2016, Vol.52 (2), pp.673-84PubMed
摘要:No study has explored the effect of yoga on cognitive decline and resting-state functional connectivity.;;This study explored the relationship between performance on memory tests and resting-state functional connectivity before and after a yoga intervention versus active con...
作者:Yang Hongyu , Wang Qiannan
来源:[J].ACS applied materials & interfaces, 2016, Vol.8 (32), pp.20635-41PubMed
摘要:Porous carbon-supported gold nanoparticles of varied sizes were prepared using thiolate-capped molecular Au25, Au38, and Au144 nanoclusters as precursors. The organic capping ligands were removed by pyrolysis at controlled temperatures, resulting in good dispersion of gold nanopa...
作者:Yang Hongyu , Jiang Xueyang ...
来源:[J].Bioorganic & medicinal chemistry, 2018PubMed
摘要:In our endeavor towards the development of potent multi-target ligands for the treatment of Alzheimer's disease, miconazole was identified to show BuChE-IDO1 dual-target inhibitory effects. Morris water maze test indicated that miconazole obviously ameliorated the cognitive funct...
作者:Yang Hongyu , Chen Yao ...
来源:[J].Journal of enzyme inhibition and medicinal chemistry, 2018, Vol.33 (1), pp.496-506PubMed
摘要:The cholinergic hypothesis has long been a "polar star" in drug discovery for Alzheimer's disease (AD), resulting in many small molecules and biological drug candidates. Most of the drugs marketed for AD are cholinergic. Herein, we report our efforts in the discovery of chol...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×