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作者:Yahdiana Harahap , Christian Samuel ...
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2016, Vol.8 (9), pp.194-200IAS
摘要:Objective: To quantify 4-hydroxycyclophosphamide in cancer patients’ plasma for therapeutic drug monitoring of cyclophosphamide.Methods: The blood was collected at 0.5 and 1 h after administration of chemotherapy. Prior to analysis, 4-OHCP in plasma was derivatized with semi...
作者:Yahdiana Harahap , Fadlina Chany Saputri ...
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2015, Vol.8 (1), pp.96-100IAS
摘要:Objective: To determine and validate of irbesartan and sinensetin simultaneously by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and application of this method to study a pharmacokinetic interaction of irbesartan and ethanol extract of Orthosiphon stamineus herb...
作者:Yahdiana Harahap , Norma Andriyani , Harmita .
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (4), pp.87-91IAS
摘要:Objective: To obtain an optimum and validated method for analyzing lercanidipine in plasma using Ultra Performance Liquid Chromatography of Tandem Mass Spectrometry (UPLC-MS/MS).Methods: The separation was carried out using 1.7μm (2.1 x 100 mm) Waters AcquityTM UPLC C18 colu...
作者:Yahdiana Harahap , Ganesya Rita Putri , Herman Suryadi
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.331-334IAS
摘要:Objective: This study aimed to determine clopidogrel in plasma to obtain its pharmacokinetic profile using ultra-high-performance liquidchromatography-tandem mass spectrometry (UPLC-MS/MS).Methods: Clopidogrel analysis was performed in vivo by UPLC-MS/MS using validated meth...
作者:Yahdiana Harahap , Prastiwi Arum Sari , Catur Jatmika
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.126-129IAS
摘要:Objective: This study aimed to develop an analytical method for determining metformin concentrations in human dried blood spots (DBS) usingoptimal chromatographic conditions and DBS preparation methods and validate the analytical methods.Methods: Analysis metformin HCl perfo...
作者:Yahdiana Harahap , Nathania Leony ...
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.370-375IAS
摘要:Objective: This study was aimed to develop a highly sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) methodfor the simultaneous quantification of tamoxifen, endoxifen, and clomiphene (internal standard) levels in human plasma.Methods: Plasma ...
作者:Yahdiana Harahap , Anisa Maulidina , Delly Ramadon
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.392-395IAS
摘要:Objective: The aim of this study was to optimize and validate a plasma clopidogrel analysis method using liquid chromatography tandem-massspectrometry.Methods: Plasma samples were analyzed using a BEH C18 column (1.7 μm; 100 mm×2.1 mm), the mobile phase was 0.1% formic acid ...
作者:Yahdiana Harahap , Citra Dara Malia , Sunarsih .
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.354-357IAS
摘要:Objective: This study aimed to analyze the metformin hydrochloride in dried blood spot (DBS) sample and evaluate a pharmacokinetic profile in sixhealthy subjects who administered 850-mg metformin hydrochloride in tablet using high-performance liquid chromatography–photodiode...
作者:Yahdiana Harahap , Dimas Agus Putera Hardijanto , Delly Ramadon
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.200-202IAS
摘要:Objective: This study aimed to determine the effects of the method of internal standard addition, spotting volume, paper type, and sample storagetemperature on 6-mercaptopurine, and 6-thioguanine on liquid chromatography tandem-mass spectrometry (LC-MS/MS) bioanalysis method...
作者:Yahdiana Harahap , Cheputri Rahma Astrini , Herman Suryadi
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.412-415IAS
摘要:Objective: This study aimed to obtain an optimal and validated method of analyzing 6-mercaptopurine (6-MP) and 6-thioguanine (6-TG) simultaneouslyin dried blood spot samples using ultra high-performance liquid chromatography-tandem mass spectrometry.Method: Separation was pe...

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