PubMed期刊
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作者:Xiao Kang , Wang Jing ...
来源:[J].Scientific reports(IF 2.927), 2019, Vol.9 (1), pp.1836PubMed
摘要:Genetic Creutzfeldt-Jakob disease (gCJD) with E200K mutation is one of the common subtypes of human genetic prion diseases worldwide. In this study, we systematically analyzed 30 Chinese E200K gCJD cases for their epidemiological, clinical, laboratory and genetic features. The pa...
作者:Xiao Kang , Xu Lin ...
来源:[J].PloS one(IF 3.73), 2016, Vol.11 (9), pp.e0162861PubMed
摘要:The gene encoding phosphopantetheinyl transferase (PPTase), pfaE, a component of the polyketide synthase (PKS) pathway, is crucial for the production of docosahexaenoic acid (DHA, 22:6ω3), along with the other pfa cluster members pfaA, pfaB, pfaC and pfaD. DHA was produced i...
作者:Xiao Kang , Zhang Xiu-Chun ...
来源:[J].PloS one(IF 3.73), 2015, Vol.10 (10), pp.e0139552PubMed
摘要:To identify the features of Chinese genetic prion diseases.;;Suspected Creutzfeldt-Jakob disease (CJD) cases that were reported under CJD surveillance were diagnosed and subtyped using the diagnostic criteria issued by the WHO. The general information concerning the patient, thei...
作者:Xiao Kang , Dong Yi-Chen ...
来源:[J].Diabetes therapy : research, treatment and education of diabetes and related disorders, 2019, Vol.10 (5), pp.1859-1868PubMed
摘要:INTRODUCTION(#br)Pars plana vitrectomy (PPV) is considered to be an essential and effective surgical approach for the management of complications of diabetic retinopathy. Given the high rate of accelerated cataract progression after PPV, PPV combined with cataract surgery appears...
作者:Xiao Kang , Zhou Wei ...
来源:[J].Journal of clinical neurology (Seoul, Korea)(IF 1.892), 2019PubMed
摘要:BACKGROUND AND PURPOSE(#br)Gerstmann-Sträussler-Scheinker disease (GSS) with a proline-to-leucine mutation at codon 102 (P102L) in the PRNP gene is the most frequently reported GSS subtype worldwide. This study aimed to determine the epidemiological, clinical, genetic, and l...
作者:Xiao Kang , Hu Chao ...
来源:[J].ACS chemical neuroscience(IF 3.871), 2019, Vol.10 (10), pp.4293-4302PubMed
摘要:The linkage between mitochondrial dysfunction and neurodegenerative diseases including prion diseases has been frequently reported. As the major deacetylase in mitochondria, SIRT3 plays a crucial part in regulating the function of many mitochondrial proteins. Although SIRT3 ...
作者:Xiao Kang , Wang Jing ...
来源:[J].ACS chemical neuroscience(IF 3.871), 2019, Vol.10 (3), pp.1273-1283PubMed
摘要:Activation of microglia and increased expression of TNF-α are frequently observed in the brains of human and animal prion diseases. As an important cytokine, TNF-α participates in not only pro-inflammatory responses but also in cellular communication, cell differentiation, a...
作者:Xiao Kang , Sun Jing ...
来源:[J].Infectious diseases of poverty, 2016, Vol.5 (1), pp.35PubMed
摘要:The aim of this study was to analyze the state of activity and levels of complement in the cerebrospinal fluid (CSF) of patients with various prion diseases (PrDs).;;The proteomic data emphasized the levels of 20 known complement components found in the CSF of the sCJD panel...
作者:Xiao Kang , Lei Wen-Wen ...
来源:[J].Infectious diseases of poverty, 2016, Vol.5 (1), pp.62PubMed
摘要:The outbreak of Ebola virus disease (EVD) in West Africa between 2014 and 2015 was the largest EDV epidemic since the identification of Ebola virus (EBOV) in 1976, and the countries most strongly affected were Sierra Leone, Guinea, and Liberia.;;The Sierra Leone-China Friendship ...
作者:Xiao Kang , Lei Wen Wen ...
来源:[J].Biomedical and environmental sciences : BES(IF 1.154), 2016, Vol.29 (6), pp.443-7PubMed
摘要:Ebola virus disease reemerged in Western Africa in 2014. Chinese Center for Disease Control and Prevention dispatched the first Ebola virus (EBOV) detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory. The aims of study were to underst...

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