PubMed期刊
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作者:Wu Dan-Dan , Lau Andy T Y
来源:[J].PloS one(IF 3.73), 2016, Vol.11 (8), pp.e0159801PubMed
摘要:Sirtuin-3 (SIRT3) is a major mitochondrial NAD(+)-dependent deacetylase and plays a key role in the progression and development of human cancers. Although the prognostic and clinicopathological features of SIRT3 expression in various cancers have been investigated by different re...
作者:Wu Dan-Dan , Chen Xi ...
来源:[J].Molecular cancer(IF 5.134), 2017, Vol.16 (1), pp.138PubMed
摘要:There is increasing evidence in support of the role of lncRNAs in tumor cell proliferation, differentiation and apoptosis.;;We examined the expression of the lncRNA ABHD11-AS1 in epithelial ovarian cancer (EOC) tissues and normal ovarian tissues by real-time quantitati...
作者:Wu Dan-Dan , Sang Xiu-Bo ...
来源:[J].Cell death & disease(IF 6.044), 2017, Vol.8 (10), pp.e3118PubMed
摘要:Highly upregulated in liver cancer (HULC) is a long noncoding RNA (lncRNA), which has recently been identified as a key regulator in the progression of hepatocellular carcinoma, gliomas and gastric cancer. However, its role in epithelial ovarian carcinoma (EOC) remains unknown. I...
作者:Wu Dan-Dan , Hu Hong-Tao ...
来源:[J].Science China. Life sciences, 2019PubMed
摘要:We conducted a retrospective cohort study of 9,552 women experiencing their second delivery between 2014 and 2016 at the International Peace Maternity and Child Health Hospital to investigate the association between the interpregnancy interval (IPI) and adverse perinatal out...
作者:Wu Dan-Dan , Zheng Wei ...
来源:[J].Oncotarget(IF 6.636), 2016, Vol.7 (5), pp.6146-58PubMed
摘要:Protein array technology is a powerful platform for the simultaneous determination of the expression levels of a number of proteins as well as post-translational modifications such as phosphorylation. Here, we screen and report for the first time, the dominant signaling casc...
作者:Wu Dan-Dan , Lau Andy T Y ...
来源:[J].Oncotarget(IF 6.636), 2017, Vol.8 (30), pp.49144-49155PubMed
摘要:Extracellular signal-regulated kinase 8 (ERK8), also known as mitogen-activated protein kinase 15 (MAPK15), is the most recently identified protein kinase of the ERK family members and yet the least has been studied so far. Here, we report that ERK8 is highly expressed in se...
作者:Wu Dan-Dan , Meng Ling-Qi ...
来源:[J].Oncotarget(IF 6.636), 2017, Vol.8 (70), pp.115398-115412PubMed
摘要:Cryptotanshinone (CT), isolated from the plant Salvia miltiorrhiza Bunge , has been reported to have potential anticancer effects on human prostate and breast cancer cells. However, the mechanisms of action of CT on gastric cancer (GC) cells are not well understood. Here we inves...
作者:Wu Dan-Dan , Gao Ling ...
来源:[J].Oncotarget(IF 6.636), 2016, Vol.7 (52), pp.86511-86521PubMed
摘要:Infants being born Large-for-gestational-age (LGA) are prone to developing cardiometabolic disease. However, the underlying mechanisms remain unclear.;;Clinical investigation showed that children born LGA had significantly higher serum level of total cholesterol (TC), low-de...
作者:Wu Dan-Dan , Zhang Ji-Xiang ...
来源:[J].World journal of gastroenterology, 2018, Vol.24 (17), pp.1901-1910PubMed
摘要:To investigate the antitumor activity of α-hederin in hepatocellular carcinoma (HCC) cells and its underlying mechanisms in vitro and in vivo .;;SMMC-7721, HepG-2 and Huh-7 HCC cells were cultured in vitro and treated with α-hederin (0, 5 μmol/L, 10 μmol/L, 15 μmol/L, 2...
作者:Wu Dan-Dan , Mo Hai-Ying ...
来源:[J].Cells, 2019, Vol.8 (8)PubMed
摘要:Cadmium (Cd) is a widespread environmental pollutant and carcinogen. Although the exact mechanisms of Cd-induced carcinogenesis remain unclear, previous acute/chronic Cd exposure studies have shown that Cd exerts its cytotoxic and carcinogenic effects through multiple mechanisms,...

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