Wiley期刊
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作者:Thomas P. Johnston , Giuseppe Derosa ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2017, Vol.232 (7), pp.1660-1668Wiley
摘要:Exosomes are naturally occurring extracellular vesicles released by most mammalian cells in all body fluids. Exosomes are known as key mediators in cell‐cell communication and facilitate the transfer of genetic and biochemical information between distant cells. Structurally,...
作者:... Matteo Pirro , Thomas P. Johnston , Amirhosein Sahebkar
来源:[J].BioFactors(IF 3.088), 2017, Vol.43 (3), pp.331-346Wiley
摘要:Abstract(#br)Curcumin, the bioactive polyphenolic ingredient of turmeric, has been extensively studied for its effects on human papilloma virus (HPV) infection as well as primary and malignant squamous cervical cancers. HPV infections, especially those related to HPV 16 and ...
作者:... Ramin Khameneh Bagheri , Thomas P. Johnston , Amirhossein Sahebkar
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (6), pp.4497-4511Wiley
摘要:Atherothrombotic cardiovascular disease is a major cause of mortality throughout the world. Platelet activation and aggregation play a central role in hemostasis and thrombosis. Herbal medicines have been traditionally used in the management of cardiovascular disease and can...
作者:... Amir Abbas Momtazi , Thomas P. Johnston , Amirhossein Sahebkar
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2), pp.830-848Wiley
摘要:Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities. Novel animal and human studies indicate that curcumin can affect different immune cells, such as various T lymphocyte subsets, macrophages, dendritic cells, B lymphocytes and natural kil...
作者:Thomas P. Johnston , Alexander P. Lykov ...
来源:[J].Journal of Pharmacy and Pharmacology(IF 2.033), 2016, Vol.68 (12), pp.1516-1526Wiley
摘要:Abstract(#br)Objectives(#br)We evaluated the hypolipidaemic effect of mannan Candida albicans serotype A, relative to atorvastatin, in a mouse model of hyperlipidaemia.(#br)Methods(#br)Mannan serotype A was investigated in vitro and in vivo to determine its effects on macrop...
作者:Thomas P. Johnston , Maciej Banach ...
来源:[J].Journal of Cellular Biochemistry(IF 3.062), 2017, Vol.118 (12), pp.4170-4182Wiley
摘要:ABSTRACT(#br)Curcumin, the bioactive component of turmeric, has been used for the treatment of several diseases including diabetes and its complications. Curcumin has been shown to exert pleiotropic effects by modulating different signaling molecules, including transcription...
作者:Thomas P. Johnston , Masakazu Shinohara ...
来源:[J].Journal of Pharmacy and Pharmacology(IF 2.033), 2012, Vol.64 (5), pp.677-687Wiley
摘要:Abstract(#br)Objectives There is an inverse relationship between high‐density lipoprotein (HDL) and heart disease. HDL possesses not only both antioxidant and anti‐inflammatory properties, but also anti‐thrombotic and endothelial function‐promoting qualities. However, i...
作者:Thomas P. Johnston , David J. Waxman
来源:[J].Journal of Pharmacy and Pharmacology(IF 2.033), 2008, Vol.60 (6), pp.753-759Wiley
摘要:Abstract(#br)The copolymer surfactant poloxamer 407 (P‐407) has been used to induce a dose‐controlled dyslipidaemia in both mice and rats. Human macrophages cultured with P‐407 exhibit a concentration‐dependent reduction in cholesterol efflux to apolipoprotein A1 (apoA1...
作者:Thomas P. Johnston , Kamesh R. Kuchimanchi ...
来源:[J].Journal of Pharmacy and Pharmacology(IF 2.033), 2003, Vol.55 (8), pp.1083-1090Wiley
摘要:Abstract(#br)The aim of our study was to induce changes in the plasma elimination half‐life (t1/2 elim), rate and extent of urinary excretion, and biodistribution of a model macromolecule, poly‐l‐lysine, in rats following complexation with heparin. Male Sprag...
作者:Thomas P. Johnston , Ira J. Goldberg
来源:[J].Journal of Pharmacy and Pharmacology(IF 2.033), 2006, Vol.58 (8), pp.1099-1105Wiley
摘要:Abstract(#br)This investigation was conducted to evaluate whether poloxamer 407 (P‐407), a nonionic surface‐active‐agent that functions as a lipase inhibitor, could aid in weight loss by inactivating pancreatic lipase (PL) following oral administration to mice. Using a ...

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