European Cells and Materials (eCM)
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作者:... D W Grijpma , T F Moriarty , D Eglin
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.151-164European Cells and Materials (eCM)
摘要:Antibiotic-loaded biomaterials (ALBs) have emerged as a potential useful adjunctive antimicrobial measure for the prevention of infection in open fracture care. A biodegradable thermo-responsive poly(N-isopropylacrylamide) grafted hyaluronic acid (HApN) hydrogel loaded with genta...
作者:T F Moriarty , R G Richards ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.184-199European Cells and Materials (eCM)
摘要:A fracture-related infection (FRI) is an important complication that can lead to an increase in morbidity, mortality and economic costs. Preclinical in vivo models are critical in the evaluation of novel prevention and treatment strategies, yet it is important that these studies ...
作者:T F Moriarty , T Schmid ...
来源:[J].Eur Cell Mater(IF 4.558), 2017, Vol.34, pp.83-98European Cells and Materials (eCM)
摘要:The treatment of chronic orthopaedic device-associated infection (ODRI) often requires multiple surgeries and prolonged antibiotic therapy. Despite this extensive treatment protocol, the procedure is associated with significant failure rates. Currently, no large animal model is a...
作者:... D Nehrbass , R G Richards , T F Moriarty
来源:[J].Eur Cell Mater(IF 4.558), 2017, Vol.34, pp.321-340European Cells and Materials (eCM)
摘要:Fracture-related infection (FRI) is a major complication in surgically fixed fractures. Instability of the fracture after fixation is considered a risk factor for infection; however, few experimental data are available confirming this belief. To study whether stable fractures led...
作者:... I Zderic , R G Richards , T F Moriarty
来源:[J].Eur Cell Mater(IF 4.558), 2015, Vol.30, pp.148-162European Cells and Materials (eCM)
摘要:The local mechanical environment at a fracture is known to influence biological factors such as callus formation, immune cell recruitment and susceptibility to infection. Infection models incorporating a fracture are therefore required to evaluate prevention and treatment of infe...
作者:T F Moriarty , D W Grainger , R G Richards
来源:[J].Eur Cell Mater(IF 4.558), 2014, Vol.28, pp.112-128European Cells and Materials (eCM)
摘要:Infections related to implanted medical devices have become a significant health care issue in recent decades. Increasing numbers of medical devices are in use, often in an aging population, and these devices are implanted against a background of increasing antibiotic-resistant b...

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