国际光学工程学会
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作者:Sylvia Lam , Anita Carraro ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (6), pp.066001-066001SPIE
摘要:A fiber optic imaging approach is presented using structured illumination for quantification of almost pure epithelial backscattering. We employ multiple spatially modulated projection patterns and camera-based reflectance capture to image depth-dependent epithelial scattering. T...
作者:Sylvia Lam , Calum MacAulay ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (6), pp.065002-065002SPIE
摘要:We developed a multifiber optical probe for oblique polarized reflectance spectroscopy (OPRS) in vivo and evaluated its performance in detection of dysplasia in the oral cavity. The probe design allows the implementation of a number of methods to enable depth resolved spectr...
作者:Sylvia Lam , Marette Lee ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (12)SPIE
摘要:Current diagnostic capabilities and limitations of fluorescence endomicroscopy in the cervix are assessed by qualitative and quantitative image analysis. Four cervical tissue types are investigated: normal columnar epithelium, normal and precancerous squamous epithelium, and stro...
作者:Sylvia Lam , Pierre Lane ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (8), pp.086005-086005SPIE
摘要:Dual-mode endomicroscopy is a diagnostic tool for early cancer detection. It combines the high-resolution nuclear tissue contrast of fluorescence endomicroscopy with quantified depth-dependent epithelial backscattering as obtained by diffuse optical microscopy. In an in vivo pilo...

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