国际光学工程学会
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作者:... Junjie Yao , Jan Laufer , Sarah E. Bohndiek
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (7), pp.070901-070901SPIE
摘要:Genetically encoded contrast in photoacoustic imaging (PAI) is complementary to the intrinsic contrast provided by endogenous absorbing chromophores such as hemoglobin. The use of reporter genes expressing absorbing proteins opens the possibility of visualizing dynamic cellular a...
作者:... Kevin M. Brindle , Rebecca C. Fitzgerald , Sarah E. Bohndiek
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (8), pp.084001-084001SPIE
摘要:Barrett’s esophagus is a known precursor lesion to esophageal adenocarcinoma. In these patients, early detection of premalignant disease, known as dysplasia, allows curative minimally invasive endoscopic therapy, but is confounded by a lack of contrast in white light endosco...
作者:Marcel Gehrung , Sarah E. Bohndiek , Joanna Brunker
来源:[J].Journal of Biomedical Optics(IF 2.881), 2019, Vol.24 (12), pp.121908-121908SPIE
摘要:Photoacoustic tomography (PAT) is intrinsically sensitive to blood oxygen saturation (sO2) in vivo . However, making accurate sO2 measurements without knowledge of tissue- and instrumentation-related correction factors is extremely challenging. We have devel...
作者:... Rebecca C. Fitzgerald , Timothy D. Wilkinson , Sarah E. Bohndiek
来源:[J].Journal of Biomedical Optics(IF 2.881), 2019, Vol.24 (12), pp.126004-126004SPIE
摘要:Phase and polarization of coherent light are highly perturbed by interaction with microstructural changes in premalignant tissue, holding promise for label-free detection of early tumors in endoscopically accessible tissues such as the gastrointestinal tract. Flexible optical mul...

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