欧洲呼吸学会
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作者:Rozenn Quarck , Serge Adnot
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (4)ERS
摘要:Macrophages are major players in the pathogenesis of pulmonary arterial hypertension (PAH).(#br)To investigate whether lung macrophages and pulmonary-artery smooth muscle cells (PASMCs) collaborate to stimulate PASMC growth and whether the CCL2-CCR2 and CCL5-CCR5 pathways in...
作者:Rozenn Quarck , Aurélie Maillard ...
来源:[J].European Respiratory Journal(IF 6.355), 2016, Vol.48 (2), pp.470-483ERS
摘要:Pulmonary artery smooth muscle cell (PA-SMC) proliferation and inflammation are key components of pulmonary arterial hypertension (PAH). Interleukin (IL)-1β binds to IL-1 receptor (R)1, thereby recruiting the molecular adaptor myeloid differentiation primary response protein...
作者:Rozenn Quarck , Marijke Wynants ...
来源:[J].European Respiratory Journal(IF 6.355), 2015, Vol.46 (2), pp.431-443ERS
摘要:Deficient angiogenesis and systemic inflammation could be involved in the pathophysiology of chronic thromboembolic pulmonary hypertension (CTEPH). We aimed to characterise the histopathology of pulmonary vascular lesions from 52 CTEPH patients who underwent a pulmonary enda...
作者:Rozenn Quarck , Laurent Godinas ...
来源:[J].European Respiratory Review, 2019, Vol.28 (154)ERS
摘要:Pulmonary arterial hypertension is a rare and incurable chronic disease characterised by a progressive increase in pulmonary vascular resistance and right heart failure. Patient registries collecting observational data can be of great value in the understanding of clinical proble...

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