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作者:Park Soo-Hyun , Sim Yun-Beom ...
来源:[J].Archives of Pharmacal Research(IF 1.538), 2011, Vol.34 (3), pp.501-7PubMed
摘要:In the present study, the antinociceptive profiles of eugenol were examined in ICR mice. Eugenol administered orally (from 1 to 10 mg/kg) showed an antinociceptive effect in a dose-dependent manner as measured in the acetic acid-induced writhing test. Duration of antinocicep...
作者:Park Soo-Hyun , Sim Yun-Beom ...
来源:[J].Neuroscience letters, 2010, Vol.476 (3), pp.119-22PubMed
摘要:The regulation of blood glucose level in intracerebroventricular (i.c.v.) administration with opioid alone or opioid withdrawal model was studied in ICR mice. In the first group, we found that i.c.v. administered morphine or beta-endorphin alone causes an elevation of blood gluco...
作者:Park Soo-Hyun , Sim Yun-Beom ...
来源:[J].Korean Journal of Physiology and Pharmacology(IF 1), 2010, Vol.14 (5), pp.285-9PubMed
摘要:In the present study, the antinociceptive profiles of Campanula punctata extract were examined in ICR mice. The Campanula punctata contain a large dose of saponin. Campanula punctata extract administered orally (200 mg/kg) showed an antinociceptive effect as measured by the ...
作者:Park Soo-Hyun , Jung Jun-Sub ...
来源:[J].Archives of Pharmacal Research(IF 1.538), 2011, Vol.34 (2), pp.269-80PubMed
摘要:We have evaluated the possible underlying mechanisms of immobilization stress-induced analgesia (SIA) by behavioral cross-tolerance studies and molecular studies. In the behavioral studies, the cross-tolerance between single or repeated immobilization SIA and the antinocicep...
作者:... Choi Ji-Suk , Lee Seung-Hyun , Park Soo-Hyun
来源:[J].Investigative Ophthalmology & Visual Science, 2011, Vol.52 (10), pp.7267-73PubMed
摘要:Purpose. To investigate the severity and duration of desiccating stress-induced dry eye disease between mice with and without a genetic predisposition to spontaneous autoimmunity. Methods. Experimental dry eye was induced in 12- to 16-week-old wild-type C57BL/6 and autoimmun...
作者:Park Soo-Hyun , Jung Sun-Hae ...
来源:[J].Clinical Autonomic Research, 2010, Vol.20 (4), pp.229-33PubMed
摘要:Although observational studies suggest that inflammatory markers are associated with autonomic nervous system function, the causal relationship of this is not clear. We tested the hypothesis that acute inflammation will temporarily attenuate vagal reactivation as measured by hear...
作者:Park Soo-Hyun , Sim Yun-Beom ...
来源:[J].Korean Journal of Physiology and Pharmacology(IF 1), 2010, Vol.14 (3), pp.185-9PubMed
摘要:The present study demonstrates the effect of fibrates, agonists of PPARalpha on cytokines-induced proliferation in primary cultured astrocytes. Alone or combination treatment with cytokines, such as IL-1beta (10 ng/ml), IFNgamma (10 ng/ml), and TNF-alpha (10 ng/ml) cause a signif...
作者:Park Soo-Hyun , Sim Yun-Beom ...
来源:[J].Archives of Pharmacal Research(IF 1.538), 2010, Vol.33 (7), pp.1059-63PubMed
摘要:We examined the antinociceptive effect of intracerebroventricularly (i.c.v.) or intrathecally (i.t.) administered of interferon-alpha (IFN-alpha) using the tail-flick analgesic test in mice. IFN-alpha administered i.c.v. but not i.t. showed an antinociceptive effect in a dose-dep...
作者:Park Soo-Hyun , Kang Yu-Jung ...
来源:[J].Archives of Pharmacal Research(IF 1.538), 2010, Vol.33 (10), pp.1679-83PubMed
摘要:This study was done to determine the effect of stress on blood glucose regulation in ICR mice. The stress was induced by the electrical foot shock-witness model. Blood glucose level was found to be increased in the electrical foot shock-induced physical stress group. Further...
作者:Park Soo-Hyun , Shim Sun-Taek ...
来源:[J].Journal of Medicinal Food, 2010, Vol.13 (6), pp.1307-12PubMed
摘要:The present study aimed to determine the effect of black soy peptide supplementation on glucose control in subjects with prediabetes (impaired fasting glucose or impaired glucose tolerance) and newly diagnosed type 2 diabetes mellitus (DM). In this double-blind, placebo-cont...

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