视觉与眼科研究协会
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作者:Norihiro Nagai , Pete Lundh von Leithner ...
来源:[J].Investigative Ophthalmology & Visual Science, 2014, Vol.55 (6)视觉与眼科研究协会
摘要:Purpose. Characterization of a mouse model of spontaneous choroidal neovascularization (sCNV) and its effect on retinal architectureand function.
作者:Norihiro Nagai , Yuichi Oike ...
来源:[J].Investigative Ophthalmology & Visual Science, 2005, Vol.46 (8)视觉与眼科研究协会
摘要:purpose. To examine whether the angiotensin II type 1 receptor (AT1-R) signaling plays a role in ocular inflammation in endotoxin-induceduveitis (EIU). methods. EIU was induced in C57BL/6 mice by a single intraperitoneal injection of 150 μg lipopolysaccharide (LPS). Tissue l...
作者:Norihiro Nagai , Kanako Izumi-Nagai ...
来源:[J].Investigative Ophthalmology & Visual Science, 2007, Vol.48 (9)视觉与眼科研究协会
摘要:purpose. To investigate the involvement of the renin-angiotensin system (RAS) and the nuclear factor (NF)-κB pathway with diabetes-inducedretinal inflammation. methods. Six weeks after induction of diabetes, C57BL/6 mice were treated with the angiotensin II type 1 receptor (...
作者:Norihiro Nagai , Yuichi Oike ...
来源:[J].Investigative Ophthalmology & Visual Science, 2007, Vol.48 (5)视觉与眼科研究协会
摘要:purpose. Angiotensin-converting enzyme (ACE), also known as kininase II, functions not only to convert angiotensin I to angiotensinII, but also to cleave bradykinin into inactive fragments. Thus, ACE inhibition causes the tissue accumulation of bradykinin,exerting either of ...

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