PubMed期刊
期刊
会议
图书
作者:Mocchegiani Eugenio , Provinciali Mauro
来源:[J].Mediators of inflammation, 2017, Vol.2017, pp.3868545PubMed
摘要:Epidemiological studies have linked high consumption of meat with major age-related diseases including cardiovascular diseases. Abnormal postprandial increases in plasma lipids after a meat meal have been hypothesized among the pathogenetic mechanisms. However, it is still unknow...
作者:... Busco Franco , Galeazzi Roberta , Mocchegiani Eugenio
来源:[J].Age (Dordrecht, Netherlands), 2014, Vol.36 (3), pp.9656PubMed
摘要:Zinc is a relevant nutritional factor for the whole life of an organism because it affects the inflammatory/immune response and antioxidant activity, leading to a healthy state. Despite its important function, the dietary intake of zinc is inadequate in elderly. Possible int...
作者:Mocchegiani Eugenio , Romeo Javier ...
来源:[J].Age, 2013PubMed
摘要:The diet in the elderly does not provide a sufficient level of nutrients needed to maintain an adequate healthy status leading to micronutrient deficiencies and impaired immune response with subsequent development of degenerative diseases. Nutrient "zinc" is a relevant micro...
作者:Mocchegiani Eugenio , Costarelli Laura ...
来源:[J].Ageing Research Reviews, 2012, Vol.11 (2), pp.297-319PubMed
摘要:In ageing, alterations in inflammatory/immune response and antioxidant capacity lead to increased susceptibility to diseases and loss of mobility and agility. Various essential micronutrients in the diet are involved in age-altered biological functions. Micronutrients (zinc, copp...
作者:Mocchegiani Eugenio , Giacconi Robertina ...
来源:[J].New York Academy of Sciences. Annals(IF 4.375), 2004, Vol.1019, pp.127-34PubMed
摘要:The capacity of the remodeling immune responses during stress (immune plasticity) is fundamental to reach successful aging. We herein report two pivotal models to demonstrate the relevance of the immune plasticity in aging and successful aging. One model is represented by the cir...
作者:Mocchegiani Eugenio , Malavolta Marco
来源:[J].Aging Cell(IF 5.705), 2004, Vol.3 (4), pp.177-84PubMed
摘要:Immunosenescence is defined as the state of dysregulated immune function that contributes to the increased susceptibility to infection, cancer and autoimmune diseases observed in old organisms, including humans. However, dysregulations in the immune functions are normally counter...
作者:Mocchegiani Eugenio , Giacconi Robertina ...
来源:[J].Immunity & Ageing, 2005, Vol.1 (1), pp.5PubMed
摘要:BACKGROUND: With advancing age, thymic efficiency shows progressive decline due to thymic involution allowing impaired cell-mediated immunity and the appearance of age-related diseases. The intrinsic cause of thymic involution is still undefined. Chronic inflammation and high glu...
作者:Mocchegiani Eugenio , Muzzioli Mario ...
来源:[J].MECHANISMS OF AGEING AND DEVELOPMENT(IF 3.264), 2003, Vol.124 (4), pp.459-68PubMed
摘要:Metallothioneins (MTs) play pivotal role in zinc-related cell homeostasis because of their high affinity for this trace element which is in turn relevant against oxidative stress and for the efficiency of the entire immune system, including natural killer (NK) cell activity. In o...
作者:Mocchegiani Eugenio , Giacconi Robertina ...
来源:[J].Experimental Gerontology(IF 3.911), 2002, Vol.37 (2-3), pp.349-57PubMed
摘要:Metallothioneins (MTs) are involved in metal-related cell homeostasis because of their high affinity for metals forming clusters. The main functional role of MTs is to sequester and/or dispense zinc participating in zinc homeostasis, which is relevant in normal immune response. C...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×