Innovare科学出版社
期刊
会议
图书
作者:... Chiswyta Chaliana , Melva Louisa , Rianto Setiabudy
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (9), pp.87-91IAS
摘要:Objective: To develop and validate high-performance liquid chromatography with photodiode array (HPLC-PDA) detector as a method for measuring carbamazepine plasma concentrations in epilepsy patients treated with monotherapy or polytherapy.Methods: Carbamazepine was extracted...
作者:Bashar Adi Wahyu Pandhita , Vivian Soetikno , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.152-154IAS
摘要:Objective: This study aimed to investigate the effect of nanocurcumin (NC) against cisplatin-induced acute kidney injury, focusing on Nrf2 and Keap1.Methods: Male Sprague-Dawley rats (n=23) were divided into five groups (Control, CP, CP+Cur, CP+50 NC, and CP+100 NC) and sacrifice...
作者:Deliana Nur Ihsani Rahmi , Melva Louisa , Vivian Soetikno
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.172-174IAS
摘要:Objective: This study aimed to investigate the efficacy of curcumin (CMN) and nanocurcumin (NC) at preventing cisplatin (CDPP)-inducednephrotoxicity.Methods: Two membrane transporters, copper transporter 1 (CTR1) and organic cation transporter 2 (OCT2), have been identified invol...
作者:... Wilson Bastian , Paramita . , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.102-105IAS
摘要:Objective: The aim of the present study was to determine whether curcumin (CM) can prevent drug sensitivity of breast cancer (BC) cells when E andβ-E2 are administered together and whether the underlying mechanism involves modulation of drug efflux transporters.Methods: MCF7...
作者:... Lies Sugiarti , Septelia Inawati Wanandi , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.335-337IAS
摘要:Objective: This study was designed to analyze the role of piperine in modulating P-glycoprotein mRNA expression when added in combination withtamoxifen to breast cancer cells in culture.Methods: MCF-7 breast cancer cells were treated with 1 μM tamoxifen with or without piper...
作者:MELVA LOUISA , HENDRI ASTUTY ...
来源:[J].International Journal of Applied Pharmaceutics, 2019, pp.172-176IAS
摘要:Objective: This study aimed to determine the potential inhibitory effects of Eleutherine bulbosa on the growth of Plasmodium falciparum and its toxiceffects on lymphocyte cells.Methods: We performed a 50% inhibition concentration (IC50) test of E. bulbosa against P. falcipar...
作者:... KELVIN THEANDRO GOTAMA , VIVIAN SOETIKNO , MELVA LOUISA
来源:[J].International Journal of Applied Pharmaceutics, 2019, pp.164-167IAS
摘要:Objective: Alcohol accumulation in the liver can cause pathological disorders such as liver fibrosis that can develop into hepatocellular carcinoma,one of the main causes of mortality associated with liver disease. The previous studies have shown that a plant compound, alpha...
作者:... YUYUNTIA YUYUNTIA , VIVIAN SOETIKNO , MELVA LOUISA
来源:[J].International Journal of Applied Pharmaceutics, 2019, pp.177-180IAS
摘要:Objective: Alpha-mangostin (α-MG) has been shown to possess antifibrotic effects. However, the specific mechanism of action of this compoundremains poorly understood. Therefore, the aim of this study was to investigate the effect of α-MG on the expression levels of transform...
作者:MELVA LOUISA , BANTARI WK WARDHANI
来源:[J].International Journal of Applied Pharmaceutics, 2019, pp.168-171IAS
摘要:Objectives: In various liver disease models, including those for alcoholic liver diseases, curcumin, a polyphenolic compound derived fromCurcuma longa, is known to have an hepatoprotective effect. However, the mechanism of action underlying its effects on alcohol-induced hep...
作者:... VIVIAN SOETIKNO , MELVA LOUISA , WAWAIMULI AROZAL
来源:[J].International Journal of Applied Pharmaceutics, 2019, pp.230-233IAS
摘要:Objective: The antineoplastic agent doxorubicin (DOX) is known for causing liver toxicity. Its metabolism in hepatocytes causes oxidative stress, which,in turn, induces DNA damage, lipid peroxidation, ATP depletion, and apoptosis. L-citrulline (CIT), a commonly found agent i...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×