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作者:... Chiswyta Chaliana , Melva Louisa , Rianto Setiabudy
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (9), pp.87-91IAS
摘要:Objective: To develop and validate high-performance liquid chromatography with photodiode array (HPLC-PDA) detector as a method for measuring carbamazepine plasma concentrations in epilepsy patients treated with monotherapy or polytherapy.Methods: Carbamazepine was extracted...
作者:Bashar Adi Wahyu Pandhita , Vivian Soetikno , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.152-154IAS
摘要:Objective: This study aimed to investigate the effect of nanocurcumin (NC) against cisplatin-induced acute kidney injury, focusing on Nrf2 and Keap1.Methods: Male Sprague-Dawley rats (n=23) were divided into five groups (Control, CP, CP+Cur, CP+50 NC, and CP+100 NC) and sacrifice...
作者:Deliana Nur Ihsani Rahmi , Melva Louisa , Vivian Soetikno
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.172-174IAS
摘要:Objective: This study aimed to investigate the efficacy of curcumin (CMN) and nanocurcumin (NC) at preventing cisplatin (CDPP)-inducednephrotoxicity.Methods: Two membrane transporters, copper transporter 1 (CTR1) and organic cation transporter 2 (OCT2), have been identified invol...
作者:... Wilson Bastian , Paramita . , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.102-105IAS
摘要:Objective: The aim of the present study was to determine whether curcumin (CM) can prevent drug sensitivity of breast cancer (BC) cells when E andβ-E2 are administered together and whether the underlying mechanism involves modulation of drug efflux transporters.Methods: MCF7...
作者:... Lies Sugiarti , Septelia Inawati Wanandi , Melva Louisa
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (1), pp.335-337IAS
摘要:Objective: This study was designed to analyze the role of piperine in modulating P-glycoprotein mRNA expression when added in combination withtamoxifen to breast cancer cells in culture.Methods: MCF-7 breast cancer cells were treated with 1 μM tamoxifen with or without piper...

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