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作者:... Paul Kumar Upputuri , Chenjie Xu , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041007-041007SPIE
摘要:Photoacoustic imaging has become an emerging tool for theranostic applications. Not only does it help in in vivo , noninvasive imaging of biological structures at depths but it can also be used for drug release and therapeutic applications. We explore near-infrared light-sensitiv...
作者:... Vijitha Periyasamy , Kew Kok Wen , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041008-041008SPIE
摘要:Translating photoacoustic (PA) imaging into clinical setup is a challenge. We report an integrated PA and ultrasound imaging system by combining the light delivery to the tissue with the ultrasound probe. First, Monte Carlo simulations were run to study the variation in absorbanc...
作者:Paul Kumar Upputuri , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041006-041006SPIE
摘要:Photoacoustic imaging is an emerging hybrid imaging modality that can provide multicontrast, multiscale imaging of biological features ranging from organelles to organs. The three major embodiments of photoacoustic imaging are microscopy, endoscopy, and computed tomography. Photo...
作者:Sandeep Kumar Kalva , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (2), pp.026009-026009SPIE
摘要:A typical photoacoustic tomography (PAT) system uses a Q-switched Nd:YAG laser for irradiating the sample and a single-element ultrasound transducer (UST) for acquiring the photoacoustic data. Conventionally, in PAT systems, the UST is held in a horizontal position and moved...
作者:Paul Kumar Upputuri , Moganasundari Krisnan , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.045001-045001SPIE
摘要:Optical resolution photoacoustic microscopy (ORPAM) is a high-resolution hybrid imaging modality having potential for microscale in vivo imaging. Optical diffraction limits the lateral resolution of ORPAM. A photonic nanojet (PNJ) was used to break this diffraction limit. A ...
作者:... Sandeep Kumar Kalva , Manojit Pramanik , Phaneendra K. Yalavarthy
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (7), pp.071204-071204SPIE
摘要:As limited data photoacoustic tomographic image reconstruction problem is known to be ill-posed, the iterative reconstruction methods were proven to be effective in terms of providing good quality initial pressure distribution. Often, these iterative methods require a large numbe...
作者:... Sandeep Kumar Kalva , Manojit Pramanik , Phaneendra K. Yalavarthy
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (9), pp.091413-091413SPIE
摘要:Several algorithms exist to solve the photoacoustic image reconstruction problem depending on the expected reconstructed image features. These reconstruction algorithms promote typically one feature, such as being smooth or sharp, in the output image. Combining these features usi...
作者:... Sandeep Kumar Kalva , Manojit Pramanik , Phaneendra K. Yalavarthy
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (10), pp.100502-100502SPIE
摘要:Photoacoustic tomography tends to be an ill-conditioned problem with noisy limited data requiring imposition of regularization constraints, such as standard Tikhonov (ST) or total variation (TV), to reconstruct meaningful initial pressure rise distribution from the tomographic ac...
作者:... Zhuo-Bin Wen , Zhe Wu , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (11), pp.116003-116003SPIE
摘要:Optical resolution photoacoustic microscopy (ORPAM) is important for various biomedical applications, such as the study of cellular structures, microcirculation systems, and tumor angiogenesis. However, the lateral resolution of a conventional ORPAM is limited by optical dif...
作者:Vijitha Periyasamy , Manojit Pramanik
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (4), pp.045003-045003SPIE
摘要:Monte Carlo modeling of light transport in multilayered tissue (MCML) is modified to incorporate objects of various shapes (sphere, ellipsoid, cylinder, or cuboid) with a refractive-index mismatched boundary. These geometries would be useful for modeling lymph nodes, tumors, bloo...

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