PubMed期刊
期刊
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作者:Malavolta Marco , Bracci Massimo ...
来源:[J].Mediators of inflammation, 2018, Vol.2018, pp.4159013PubMed
摘要:The reactivation of senescence in cancer and the subsequent clearance of senescent cells are suggested as therapeutic intervention in the eradication of cancer. Several natural compounds that activate Nrf2 (nuclear factor erythroid-derived 2-related factor 2) pathway, which is in...
作者:... Mocchegiani Eugenio , Provinciali Mauro , Malavolta Marco
来源:[J].Mediators of inflammation, 2017, Vol.2017, pp.3868545PubMed
摘要:Epidemiological studies have linked high consumption of meat with major age-related diseases including cardiovascular diseases. Abnormal postprandial increases in plasma lipids after a meat meal have been hypothesized among the pathogenetic mechanisms. However, it is still unknow...
作者:... Giacconi Robertina , Costarelli Laura , Malavolta Marco
来源:[J].Biogerontology, 2016, Vol.17 (4), pp.703-14PubMed
摘要:Impairment of one or more parameters of circadian rhythms (CR) of body temperature (BT) and locomotor activity (LMA) are considered among the hallmarks of mammalian aging. These alterations are frequently used as markers for imminent death in laboratory mice. However, there are s...
作者:Malavolta Marco , Basso Andrea ...
来源:[J].Age (Dordrecht, Netherlands), 2014, Vol.36 (3), pp.9656PubMed
摘要:Zinc is a relevant nutritional factor for the whole life of an organism because it affects the inflammatory/immune response and antioxidant activity, leading to a healthy state. Despite its important function, the dietary intake of zinc is inadequate in elderly. Possible int...
作者:Malavolta Marco , Basso Andrea ...
来源:[J].Biogerontology, 2017, Vol.18 (2), pp.217-236PubMed
摘要:Recent evidence suggests that high dose and/or long term use of proton pump inhibitors (PPIs) may increase the risk of adverse cardiovascular events in older patients, but mechanisms underlying these detrimental effects are not known. Taking into account that the senescent endoth...
作者:Malavolta Marco , Calabrese Roberta ...
来源:[J].Aging cell, 2016, Vol.15 (4), pp.755-65PubMed
摘要:Aging is associated with alterations in the content and patterns of DNA methylation virtually throughout the entire human lifespan. Reasons for these variations are not well understood. However, several lines of evidence suggest that the epigenetic instability in aging may be tra...
作者:Malavolta Marco , Piacenza Francesco
来源:[J].BioFactors (Oxford, England), 2017, Vol.43 (6), pp.770-784PubMed
摘要:Impaired zinc homeostasis is observed in diabetes mellitus (DM2) and its complications. Zinc has a specific role in pancreatic β-cells via insulin synthesis, storage, and secretion. Intracellular zinc homeostasis is tightly controlled by zinc transporters (ZnT and Zip famili...
作者:Malavolta Marco , Zampieri Michele ...
来源:[J].The journals of gerontology. Series A, Biological sciences and medical sciences, 2017PubMed
摘要:Down syndrome (DS) is caused by the presence of part or an entire extra copy of chromosome 21, a phenomenon that can cause a wide spectrum of clinically defined phenotypes of the disease. Most of the clinical signs of DS are typical of the ageing process including dysregulation o...
作者:Malavolta Marco , Piacenza Francesco ...
来源:[J].Analytical Biochemistry, 2011, Vol.421 (1), pp.16-25PubMed
摘要:Speciation analysis of essential trace elements in human serum provides important information on nutritional status and homeostatic mechanisms regulating transport processes, acute phase reactions, and protection against oxidative damage. Anion exchange high-performance liquid ch...

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