PubMed期刊
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作者:Malavolta Marco , Giacconi Robertina ...
来源:[J].Biogerontology(IF 3.19), 2010, Vol.11 (3), pp.309-19PubMed
摘要:Associations have been reported between plasma Cu and Zn levels and the incidence of the most important age-related diseases. Previously proposed methods of using plasma Cu/Zn as a predictor of all-cause mortality have been derived from populations in which old and very old subje...
作者:Malavolta Marco , Cipriano Catia ...
来源:[J].Rejuvenation Research(IF 2.919), 2008, Vol.11 (2), pp.455-9PubMed
摘要:It is known that metallothionein (MT) mRNA expression first increases with age, but then decreases again in the very elderly. Here we report that MT protein levels also decrease in very old age, and that this is independent of dietary zinc intake. Age-related changes of MT, as we...
作者:Malavolta Marco , Costarelli Laura ...
来源:[J].Cytometry. Part A(IF 3.711), 2006, Vol.69 (10), pp.1043-53PubMed
摘要:: The amount of available intracellular zinc is pivotal to regulate many cellular processes, including oxidative stress response and apoptotic mechanisms. Therefore it is not surprising that zinc homeostasis and dyshomeostasis is involved in many physiological and pathological st...
作者:... Cipriano Catia , Malavolta Marco , Renieri Carlo
来源:[J].The Veterinary Journal, 2011PubMed
摘要:The aim of this study was to validate an A/T single nucleotide polymorphism (SNP) corresponding to a LINE2 sequence located ∼1.1kb downstream of the IL-6 gene (SNP BIEC2-911738) and to determine if this variant is correlated with interleukin 6 (IL-6) modulation or with diffe...
作者:... Piacenza Francesco , Basso Andrea , Malavolta Marco
来源:[J].Biogerontology(IF 3.19), 2011, Vol.12 (5), pp.455-65PubMed
摘要:Ageing is an inevitable biological process associated with gradual and spontaneous biochemical and physiological changes and increased susceptibility to diseases. Nutritional factor, zinc, known to be involved in improving immunity, may remodel some of the age-associated changes,...
作者:Malavolta Marco , Lattanzio Fabrizia ...
来源:[J].Age, 2012PubMed
摘要:Associations between copper to zinc ratio (CZr) and mortality have suggested CZr as a biomarker of aging. Nevertheless, very limited data exist on the association between serum CZr and physical or functional status of very old people. We examined the relationship between serum CZ...
作者:Malavolta Marco , Giacconi Robertina ...
来源:[J].The Journal of Nutritional Biochemistry, 2009, Vol.21 (6), pp.526-31PubMed
摘要:Although zinc plays an important role in health status of the elderly, their dietary habits in relation to zinc intake are not well documented. The main objective of the current study was the assessment of dietary zinc intake in European old populations and the investigation of i...
作者:Malavolta Marco , Cipriano Catia ...
来源:[J].The Journal of Nutritional Biochemistry, 2009, Vol.21 (5), pp.432-7PubMed
摘要:Overweight and obesity are associated with low grade of inflammation and chronic inflammatory response characterized by abnormal production and activation of some pro-inflammatory signalling pathways. Taking into account that obesity is the direct result of an imbalance between e...
作者:Malavolta Marco , Richter Dimitris ...
来源:[J].The Journal of Nutritional Biochemistry, 2009, Vol.21 (10), pp.1008-14PubMed
摘要:Metallothioneins (MT), the antioxidant zinc-binding proteins, seem to mediate cardioprotection. It has been postulated that zinc homeostasis and MT function may be altered, as a consequence of oxidative stress, in cardiovascular disease (CVD), with a potential implication of MT g...
作者:Malavolta Marco , Piacenza Francesco ...
来源:[J].Rejuvenation Research, 2009, Vol.13 (2-3), pp.288-91PubMed
摘要:Neonatal thymus grafts exert a rejuvenating action on various immunological and nonimmunological functions found altered in old mice. Commonly, half of a thymus is grafted under the kidney capsule. The invasiveness of the surgical procedure and the use of limited thymus tissue ma...

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