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作者:Shweta Mishra , C. J. Patel , M. M. Patel
来源:[J].International Journal of Applied Pharmaceutics, 2017, Vol.9 (5), pp.1-8IAS
摘要:Objective: This study aims to develop and validate a stability indicating HPLC method for simultaneous estimation of sacubitril and valsartan in pharmaceutical dosage form.Methods: Sacubitril and valsartan separation were achieved by LC-20 AT C18 (250 mm x 4.6 mm) column and...
作者:Mitali V. Verma , Chirag J. Patel , M. M. Patel
来源:[J].International Journal of Applied Pharmaceutics, 2017, Vol.9 (5), pp.33-41IAS
摘要:Objective: To develop precise, accurate and reproducible stability assay method by RP-HPLC for estimation of dapagliflozin in API and pharmaceutical dosage form.Methods: The adequate separation was carried using agilent C18 (4.6 ml (millimeter)*150,5 µm (micromiter), mixture...
作者:Jahanvee K. Trivedi , Chirag J. Patel , M. M. Patel
来源:[J].International Journal of Applied Pharmaceutics, 2018, Vol.10 (5), pp.81-89IAS
摘要:Objective: To develop and validate macitentan with its known and unknown degradation impurities in its tablet dosage form.Methods: The RP-HPLC method for macitentan and its impurities was developed and three potential degradation impurities MCA-02, MCA-01 and degradation imp...

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