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作者:Luana Mota Ferreira , Vanessa AngonesiZborowski ...
来源:[J].Colloids and Surfaces B: Biointerfaces(IF 3.554), 2017, Vol.157, pp.464-472Elsevier
摘要:Abstract(#br)The p,p'-methoxyl-diphenyl diselenide [(OMePhSe)2] is an, organoselenium compound that elicits antinociceptive action in different, animal models of pain. However, the compound has physicochemical, Limitations that delay its clinical studies. Herein, (OMePhSe)2, nano...
作者:Luana Mota Ferreira , Allanna Valentini Barbieri ...
来源:[J].Materials Science & Engineering C(IF 2.404), 2017, Vol.74, pp.279-286Elsevier
摘要:Abstract(#br)This study aimed to develop poly(ε-caprolactone) nanocapsules loaded with indole-3-cabinol (I3C) using rose hip oil (RHO) or medium chain triglycerides (MCT) as oil core. In vitro radical scavenging activity (DPPH method), hemolysis, and antitumor effects on bre...
作者:Luana Mota Ferreira , Vanessa Angonesi Zborowski ...
来源:[J].European Journal of Pharmaceutics and Biopharmaceutics(IF 3.826), 2017, Vol.117, pp.39-48Elsevier
摘要:Abstract(#br)Organoselenium compounds have been targeted to new therapeutic tools development due to their pharmacological actions. However, some toxicity issues and physicochemical limitations delay the clinical application of these compounds. The incorporation of organosel...
作者:Luana Mota Ferreira , Natália Silva Jardim ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2018, Vol.111, pp.38-45Elsevier
摘要:Abstract(#br)The current study investigated the effect of organoselenium compound p , p ′-methoxyl-diphenyl diselenide [(OMePhSe) 2 ], free or incorporated into nanocapsules, on behavioral, biochemical and molecular alterations in an inflammatory pain model induced by comple...
作者:Luana Mota Ferreira , Natália da Silva Jardim ...
来源:[J].Journal of Trace Elements in Medicine and Biology(IF 1.959), 2018, Vol.46, pp.17-25Elsevier
摘要:Abstract(#br)Neuropathic pain is a public health problem and its treatment is a global challenge. The organoselenium compound p,p’ -methoxyl-diphenyl diselenide [(OMePhSe) 2 ] has a potential antinociceptive action and its incorporation into nanocapsules improves this action...
作者:Luana Mota Ferreira , Allanna Valentini Barbieri ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2018, Vol.111, pp.133-141Elsevier
摘要:Abstract(#br)This study aimed the development of nanocapsules (NCs) for oral indole-3-carbinol (I3C) administration and evaluation of antinociceptive potential of this compound in its two forms, free and nanoencapsulated, using acute pain models. NCs showed adequate physicochemic...
作者:Luana Mota Ferreira , Marcel Henrique Marcondes Sari ...
来源:[J].Colloids and Surfaces B: Biointerfaces(IF 3.554), 2016, Vol.144, pp.214-221Elsevier
摘要:Abstract(#br)The combination of pomegranate seed oil and ketoprofen in nanoemulsions aiming to improve the antinociceptive effect was evaluated according to the writhing test and Complete Freud’s Adjuvant induced paw inflammation in mice. The formulations showed adequate cha...
作者:Luana Mota Ferreira , Marcel Henrique Marcondes Sari ...
来源:[J].Colloids and Surfaces B: Biointerfaces(IF 3.554), 2016, Vol.144, pp.214-221Elsevier
摘要:Abstract(#br)The combination of pomegranate seed oil and ketoprofen in nanoemulsions aiming to improve the antinociceptive effect was evaluated according to the writhing test and Complete Freud’s Adjuvant induced paw inflammation in mice. The formulations showed adequate cha...
作者:Luana Mota Ferreira , Allanna Valentini Barbieri ...
来源:[J].Materials Science & Engineering C(IF 2.404), 2016Elsevier
摘要:Abstract(#br)This study aimed to develop poly(ε-caprolactone) nanocapsules loaded with indole-3-cabinol (I3C) using rose hip oil (RHO) or medium chain triglycerides (MCT) as oil core. In vitro radical scavenging activity (DPPH method), hemolysis, and antitumor effects on bre...

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