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作者:Lixin Lang , Weihua Li ...
来源:[J].Theranostics, 2011, Vol.1, pp.341-353Ivyspring
摘要:Direct bromination of the tyrosine residues of peptides and antibodies with bromine-76, to create probes for PET imaging, has been reported. For peptides that do not contain tyrosine residues, however, a prosthetic group is required to achieve labeling via conjugation to oth...
作者:Lixin Lang , Kai Chen ...
来源:[J].Theranostics, 2011, Vol.1, pp.220-229Ivyspring
摘要:Radiolabeled bombesin analogs are promising probes for cancer imaging of gastrin-releasing peptide receptor (GRPR). In this study, we developed 18F-labeled GRPR agonists and antagonists for positron emission tomography (PET) imaging of prostate cancer. GRPR antagonists...

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