国际光学工程学会
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作者:Hsun-Chia Hsu , Lidai Wang , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (5), pp.056004-056004SPIE
摘要:As a window on the microcirculation, human cuticle capillaries provide rich information about the microvasculature, such as its morphology, density, dimensions, or even blood flow speed. Many imaging technologies have been employed to image human cuticle microvasculature. However...
作者:... Lei Li , Mark A. Anastasio , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041018-041018SPIE
摘要:Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. If the object possesses spatially variant acoustic proper...
作者:... Alejandro Garcia-Uribe , Konstantin I. Maslov , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041017-041017SPIE
摘要:We have enhanced photoacoustic computed tomography with dry acoustic coupling that eliminates water immersion anxiety and wrinkling of the animal and facilitates incorporating complementary modalities and procedures. The dry acoustic coupler is made of a tubular elastic membrane ...
作者:... Konstantin Maslov , Li Lin , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041003-041003SPIE
摘要:While lasers have been commonly used as illumination sources in photoacoustic (PA) imaging, their high purchase and maintenance costs, as well as their bulkiness, have hindered the rapid clinical dissemination of PA imaging. With this in mind, we explore an alternative illum...
作者:... Lidai Wang , Jun Zou , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041002-041002SPIE
摘要:Optical-resolution photoacoustic microscopy (OR-PAM) offers label-free in vivo imaging with high spatial resolution by acoustically detecting optical absorption contrasts via the photoacoustic effect. We developed a compact handheld OR-PAM probe for fast photoacoustic imaging. Di...
作者:... Liren Zhu , Yuecheng Shen , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (7), pp.076017-076017SPIE
摘要:Based on the photoacoustic (PA) effect, PA tomography directly measures specific optical absorption, i.e., absorbed optical energy per unit volume. We recently developed a full-ring ultrasonic transducer array-based photoacoustic computed tomography (PACT) system for small-a...
作者:... Yang Li , Jin-Yu Shao , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041004-041004SPIE
摘要:Circulating tumor cell (CTC) clusters, arising from multicellular groupings in a primary tumor, greatly elevate the metastatic potential of cancer compared with single CTCs. High-throughput detection and quantification of CTC clusters are important for understanding the tumor met...
作者:... Terence T. W. Wong , Changhuei Yang , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (1), pp.010501-010501SPIE
摘要:Normal development of the visual system in infants relies on clear images being projected onto the retina, which can be disrupted by lens opacity caused by congenital cataract. This disruption, if uncorrected in early life, results in amblyopia (permanently decreased vision even ...
作者:... Lei Li , Liren Zhu , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (3), pp.036007-036007SPIE
摘要:Ultraviolet photoacoustic microscopy (UV-PAM) is a promising intraoperative tool for surgical margin assessment (SMA), one that can provide label-free histology-like images with high resolution. In this study, using a microlens array and a one-dimensional (1-D) array ultraso...
作者:... Ruimin Chen , Qifa Zhou , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (7), pp.076001-076001SPIE
摘要:Optical-resolution photoacoustic microscopy (OR-PAM) has demonstrated fast, label-free volumetric imaging of optical-absorption contrast within the quasiballistic regime of photon scattering. However, the limited numerical aperture of the ultrasonic transducer restricts the detec...

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