国际光学工程学会
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作者:Hsun-Chia Hsu , Lidai Wang , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (5), pp.056004-056004SPIE
摘要:As a window on the microcirculation, human cuticle capillaries provide rich information about the microvasculature, such as its morphology, density, dimensions, or even blood flow speed. Many imaging technologies have been employed to image human cuticle microvasculature. However...
作者:Lidai Wang , Jun Zou
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041002-041002SPIE
摘要:Optical-resolution photoacoustic microscopy (OR-PAM) offers label-free in vivo imaging with high spatial resolution by acoustically detecting optical absorption contrasts via the photoacoustic effect. We developed a compact handheld OR-PAM probe for fast photoacoustic imaging. Di...
作者:Lidai Wang , Yun Chen ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (8), pp.086006-086006SPIE
摘要:Super-resolution microscopy techniques—capable of overcoming the diffraction limit of light—have opened new opportunities to explore subcellular structures and dynamics not resolvable in conventional far-field microscopy. However, relying on staining with exogenous fluoresce...
作者:... Konstantin I. Maslov , Lidai Wang , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (4), pp.046007-046007SPIE
摘要:We propose a calibration-free photoacoustic (PA) method for transverse flow measurements. In this method, a pulsed periodically structured (i.e., grating patterned) optical beam is used to illuminate flowing absorptive particles in an optically scattering medium. The PA signal am...
作者:Lidai Wang , Cedric Noordam
来源:[J].Journal of Biomedical Optics(IF 2.881), 2015, Vol.20 (11), pp.116002-116002SPIE
摘要:The short focal depth of a Gaussian beam limits the volumetric imaging speed of optical resolution photoacoustic microscopy (OR-PAM). A Bessel beam, which is diffraction free, provides a long focal depth, but its side lobes deteriorate image quality when the Bessel beam is d...
作者:Lidai Wang , Junjie Yao ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2013, Vol.18 (11), pp.117003-117003SPIE
摘要:We report the development of photoacoustic flowmetry assisted by high-intensity focused ultrasound (HIFU). This novel method employs HIFU to generate a heating impulse in the flow medium, followed by photoacoustic monitoring of the thermal decay process. Photoacoustic flowme...
作者:Lidai Wang , Konstantin Maslov ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2012, Vol.17 (10), pp.106007-106007SPIE
摘要:We report the development of functional photoacoustic microscopy capable of video-rate high-resolution in vivo imaging in deep tissue. A lightweight photoacoustic probe is made of a single-element broadband ultrasound transducer, a compact photoacoustic beam combiner, and a ...
作者:Lidai Wang , Chiye Li ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2013, Vol.18 (2), pp.026003-026003SPIE
摘要:A novel photoacoustic thermometric method is presented for simultaneously imaging cells and sensing their temperature. With three-seconds-per-frame imaging speed, a temperature resolution of 0.2°C was achieved in a photo-thermal cell heating experiment. Compared to other app...
作者:Lidai Wang , Joon-Mo Yang ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2012, Vol.17 (8), pp.080505-1-080505-3SPIE
摘要:By offering images with high spatial resolution and unique optical absorption contrast, optical-resolution photoacoustic microscopy (OR-PAM) has gained increasing attention in biomedical research. Recent developments in OR-PAM have improved its imaging speed, but have to sacrific...

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