PubMed期刊
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作者:Li Wei-Yi , Zhao Ming-Wei
来源:[J].International journal of ophthalmology(IF 0.119), 2019, Vol.12 (1), pp.79-82PubMed
摘要:AIM(#br)To describe the involution patterns of vessel growth of retina through fluorescein angiography (FA) of children, who had been under treatment up to 1y previously intravitreal ranibizumab (IVR) as monotherapy for retinopathy of prematurity (ROP).(#br)METHODS(#br)This is a ...
作者:Li Wei-Yi , Xia Fang-Zhou
来源:[J].International journal of ophthalmology(IF 0.119), 2017, Vol.10 (12), pp.1812-1818PubMed
摘要:To explore the role of Pioglitazone (Pio) on a mouse model of retinal ischemia/reperfusion (I/R) injury and to elucidate the potential mechanism.;;Retinal ischemia was induced in mice by increasing the intraocular pressure, and Pio was administered 4h though periocular injec...
作者:Li Wei-Yi , Ni Wei-Wei ...
来源:[J].Journal of enzyme inhibition and medicinal chemistry, 2020, Vol.35 (1), pp.404-413PubMed
摘要:A urease inhibitor with good in vivo profile is considered as an alternative agent for treating infections caused by urease-producing bacteria such as Helicobacter pylori . Here, we report a series of N -monosubstituted thioureas, which act as effective urease inhibitors wit...
作者:Li Wei-Yi , Yi Li-Li ...
来源:[J].Bioorganic & medicinal chemistry, 2018PubMed
摘要:Two series of ω-phenoxy contained acylhydroxamic acids as novel urease inhibitors were designed and synthesized. Biological activity evaluations revealed that ω-phenoxypropinoylhydroxamic acids were more active than phenoxyacetohydroxamic acids. Out of these compounds, 3-(3,...
作者:Li Wei-Yi , Chen Hui-Min ...
来源:[J].European journal of medicinal chemistry, 2018, Vol.156, pp.126-136PubMed
摘要:A novel series of aniline-containing hydroxamic acids were designed, synthesized and evaluated as anti-virulence agents for the treatment of gastritis and gastric ulcer caused by Helicobacter pylori. In vitro enzyme-based screen together with in vivo assays and structure-act...
作者:Li Wei-Yi , Zhou Wang-Chen ...
来源:[J].Cell cycle (Georgetown, Tex.), 2018, Vol.17 (17), pp.2134-2145PubMed
摘要:NF-κB signaling pathway shows significant influence on wear particle-induced osteolysis, and this study aims to explore the underlying mechanism and the role of let-7f-5p in this process. A mouse calvarial osteolysis model was constructed with PMMA particles, and the bone ma...

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