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作者:... Ma Ying Jie , Zhou Wei , Li Gao
来源:[J].Natural product research, 2020, pp.1-10
摘要:Sanguisorba officinalis L. is a traditional herbal plant that belongs to the genus Sanguisorba and the family Rosaceae. Two new phenolic glycosides ( 1-2 ), ten known phenolics ( 3-12 ), and six known monoterpenoid glycosides ( 13-18 ) were isolated from the roots of S. offi...
作者:Li Gao , Hu Zhi-Wen ...
来源:[J].ACS chemical neuroscience(IF 3.871), 2017, Vol.8 (3), pp.454-459
摘要:Clearance of amyloid β (Aβ) by immunotherapy is one of the fancy methods to treat Alzheimer's disease (AD). However, the failure of some clinical trials suggested that there may be something ignored in the past development of immunotherapy. Pyroglutamate-3 Aβ (AβpE3-X...
作者:Li Gao , Ubong Jerome Etim ...
来源:[J].Industrial & Engineering Chemistry Research(IF 2.206), 2019
摘要:A Beta-KIT-6 (BK) micro-mesoporous composite material was assembled using zeolite Beta seed solution as raw material. BK composite contained both zeolite Beta units and three-dimensional cubic Ia3d mesostructure of KIT-6, which served as a catalyst support for hydroisomerization ...
作者:Li Gao , Wang Jiaming ...
来源:[J].Natural product research, 2019, pp.1-7
摘要:A new pentacyclic triterpenoid, 3-oxo-urs-11,13(18)-dien-28-oic acid (1), along with twelve known triterpenoids, α-amyrin (2), 19α-hydroxy-α-amyrin (3), triptohypol E (4), uvaol (5), 2α,3α-dihydroxyurs-11-en-13β,28-olide (6), 3β-hydroxyurs-11-en-13β,28-olide (7), ursoli...
作者:Li Gao , Jelinek Raz ...
来源:[J].Chemical communications (Cambridge, England), 2019, Vol.55 (97), pp.14621-14624
摘要:Glycosylation of amyloidogenic proteins enhances their solubility and reduces propensity for aggregation. We therefore, prepared tryptophan-glucosamine conjugates to modulate aggregation of tau-derived PHF6-peptide. Combined in vitro and in silico approaches indicated that these ...
作者:... Sun Jinfeng , Zhou Wei , Li Gao
来源:[J].Natural product research, 2019, Vol.33 (20), pp.3021-3024
摘要:A new flavanone glycoside, (2 S )-dihydrooroxylin A 7- O -[ β -D-apiosyl(1 → 2)]- β -D-glucoside ( 1 ), and four known compounds ( 2-5 ) were isolated from Tournefortia sibirica L. The chemical structures of these compounds were determined by 1 D and 2 D NMR and HR-ESI-MS sp...
作者:... Jin Yong , Jin Mei , Li Gao
来源:[J].Natural product research, 2018, Vol.32 (9), pp.1017-1021
摘要:A new 1,4-napthoquinone derivative, namely (S)-(-)-3-(8-hydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-(4-hydroxy-3-methoxyphenyl)-propionic acid methyl ester (1), was isolated from the roots of Juglans mandshurica Maxim. The structure was identified based on HR-ESI-MS, 1D and ...

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