Ivyspring期刊
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作者:Lei Zhu , Jin Xie ...
来源:[J].Theranostics, 2011, Vol.1, pp.18-27Ivyspring
摘要:We demonstrate the first true real-time in vivo video imaging of extracellular protease expression using an ultrafast-acting and extended-use activatable probe. This simple, one-step technique is capable of boosting fluorescent signals upon target protease cleavage as early as 30...
作者:Lei Zhu , Ying Ma ...
来源:[J].Theranostics, 2011, Vol.1, pp.341-353Ivyspring
摘要:Direct bromination of the tyrosine residues of peptides and antibodies with bromine-76, to create probes for PET imaging, has been reported. For peptides that do not contain tyrosine residues, however, a prosthetic group is required to achieve labeling via conjugation to oth...
作者:Lei Zhu , Gang Liu ...
来源:[J].Theranostics, 2011, Vol.1, pp.302-309Ivyspring
摘要:Purpose: Early assessment of tumor responses to chemotherapy could enhance treatment outcomes by ensuring that, from the beginning, treatments meet the individualized needs of patients. In this study, we applied multiple modality molecular imaging techniques to pre-clinical ...

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