PubMed期刊
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作者:Lee Han-Byul , Ahn Woo-Sung ...
来源:[J].BMC veterinary research(IF 1.861), 2016, Vol.12 (1), pp.164PubMed
摘要:Current studies report that aberrations in epigenetic regulators or chromatin modifications are related to tumor development and maintenance. EZH2 (Enhancer of zeste homolog 2) is one of the catalytic subunits of Polycomb repressive complex 2, a crucial epigenetic regulator. EZH2...
作者:Lee Han-Byul , Park Hyun-Kyu ...
来源:[J].International journal of molecular sciences(IF 2.464), 2018, Vol.19 (10)PubMed
摘要:This study aimed to evaluate the usefulness of four microRNAs (miRNAs) in an acute pancreatic injury dog model. Acute pancreatitis was induced by infusion of cerulein for 2 h (7.5 μg/kg/h). The levels of well-known miRNAs, microRNA-216a (miR-216a) and microRNA-375 (miR-375),...
作者:Lee Han-Byul , Park Hyun-Kyu ...
来源:[J].Comparative medicine(IF 1.12), 2018, Vol.68 (2), pp.148-155PubMed
摘要:Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in v...
作者:Lee Han-Byul , Park Hyun-Kyu ...
来源:[J].Comparative medicine(IF 1.12), 2019, Vol.68 (2), pp.148-155PubMed
摘要:Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in v...
作者:Lee Han-Byul , Choi Hyun-Ji ...
来源:[J].Current eye research, 2018, pp.1-7PubMed
摘要:To (i) evaluate the efficacy and safety of HL036, a tumor-necrosis factor (TNF)-α-blocking protein, in the treatment of naturally occurring canine keratoconjunctivitis sicca (KCS) and (ii) compare these features with those of 1% cyclosporine A (CsA).;;Dogs (n = 29) diagnosed...
作者:Lee Han-Byul , Choi Hyun-Ji ...
来源:[J].Regulatory toxicology and pharmacology : RTP, 2019, Vol.106, pp.7-14PubMed
摘要:This study aimed to determine the safety and tolerability of the subretinal injection of hESC-derived RPE cells at higher doses than the established clinical dose (5 × 104 cells/150 μL) by using minipigs. The hESC-derived RPE cells (60 or 120 × 104 cells/150 μL) were injecte...

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