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作者:Lee Han-Byul , Ahn Woo-Sung ...
来源:[J].BMC veterinary research(IF 1.861), 2016, Vol.12 (1), pp.164PubMed
摘要:Current studies report that aberrations in epigenetic regulators or chromatin modifications are related to tumor development and maintenance. EZH2 (Enhancer of zeste homolog 2) is one of the catalytic subunits of Polycomb repressive complex 2, a crucial epigenetic regulator. EZH2...
作者:Lee Han-Byul , Park Hyun-Kyu ...
来源:[J].Comparative medicine(IF 1.12), 2018, Vol.68 (2), pp.148-155PubMed
摘要:Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in v...
作者:Lee Han-Byul , Park Hyun-Kyu ...
来源:[J].Comparative medicine(IF 1.12), 2019, Vol.68 (2), pp.148-155PubMed
摘要:Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in v...
作者:Lee Han-Byul , Choi Hyun-Ji ...
来源:[J].Current eye research, 2018, pp.1-7PubMed
摘要:To (i) evaluate the efficacy and safety of HL036, a tumor-necrosis factor (TNF)-α-blocking protein, in the treatment of naturally occurring canine keratoconjunctivitis sicca (KCS) and (ii) compare these features with those of 1% cyclosporine A (CsA).;;Dogs (n = 29) diagnosed...

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