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作者:Leander Meuris , Nico Callewaert ...
来源:[J].Structure(IF 5.994), 2015, Vol.23 (9), pp.1621-1631Elsevier
摘要:Summary(#br)Human colony-stimulating factor 1 receptor (hCSF-1R) is unique among the hematopoietic receptors because it is activated by two distinct cytokines, CSF-1 and interleukin-34 (IL-34). Despite ever-growing insights into the central role of hCSF-1R signaling in innate and...
作者:Leander Meuris , Nico Callewaert ...
来源:[J].Structure(IF 5.994), 2015, Vol.23 (9), pp.1621-1631Elsevier
摘要:Summary(#br)Human colony-stimulating factor 1 receptor (hCSF-1R) is unique among the hematopoietic receptors because it is activated by two distinct cytokines, CSF-1 and interleukin-34 (IL-34). Despite ever-growing insights into the central role of hCSF-1R signaling in innate and...
作者:... Chiara Lonigro , Leander Meuris , Nico Callewaert
来源:[J].Current Opinion in Biotechnology(IF 7.86), 2019, Vol.60, pp.17-28Elsevier
摘要:For a long time, glycoprotein production has been limited by the inherent properties of production hosts. Glycosylation of biopharmaceuticals has been regarded as a necessary evil, often needed for protein folding or function, but also a source of heterogeneity, complicating down...

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