PubMed期刊
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作者:Le Couteur David G , Ishii Isao
来源:[J].PloS one(IF 3.73), 2016, Vol.11 (8), pp.e0160521PubMed
摘要:Hydrogen sulfide (H2S), produced by the activity of cystathionine-gamma-lyase (CSE), is a key mediator of inflammation in sepsis. The liver sinusoidal endothelial cells (LSECs) are important target and mediator of sepsis. The aim of this study was to investigate the role of ...
作者:Painter Virginia , Le Couteur David G , Waite Louise M
来源:[J].Clinical interventions in aging, 2017, Vol.12, pp.1193-1203PubMed
摘要:Dysphagia is common in people living with dementia and associated with increased risk of aspiration pneumonia, dehydration, malnutrition, and death. Treatment options are limited and the use of texture-modified food and fluids (TMF) is a widespread clinical practice. This review ...
作者:Cogger Victoria C , Mohamad Mashani , Le Couteur David G
来源:[J].Aging(IF 4.696), 2017, Vol.9 (11), pp.2237-2238PubMed
作者:... Mattson Mark P , Simpson Stephen J , Le Couteur David G
来源:[J].Clinical interventions in aging, 2017, Vol.12, pp.1419-1428PubMed
摘要:Evaluation of behavior and cognition in rodent models underpins mechanistic and interventional studies of brain aging and neurodegenerative diseases, especially dementia. Commonly used tests include Morris water maze, Barnes maze, object recognition, fear conditioning, radial arm...
作者:Le Couteur David G , Naganathan Vasi ...
来源:[J].BMJ (Clinical research ed.)(IF 17.215), 2011, Vol.343, pp.d7679PubMed
摘要:To determine the speed at which the Grim Reaper (or Death) walks.;;Population based prospective study.;;Older community dwelling men living in Sydney, Australia.;;1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project).;;Walking speed (m/s) and ...
作者:Le Couteur David G , Handelsman David J
来源:[J].Australasian journal on ageing, 2017, Vol.36 (2), pp.151-157PubMed
摘要:To explore differences between older male caregivers and non-caregivers on health status, health behaviours and well-being, including symptoms of anxiety.;;Data were collected through self-completed questionnaires and face-to-face interviews with 1705 community living men ag...
作者:Le Couteur David G , Solon-Biet Samantha ...
来源:[J].Age and ageing, 2016, Vol.45 (4), pp.443-7PubMed
摘要:Nutrition has profound effects on ageing and lifespan. Caloric restriction is the major nutritional intervention that historically has been shown to influence lifespan and/or healthspan in many animal models. Studies have suggested that a reduction in protein intake can also incr...
作者:Le Couteur David G , Hirani Vasant ...
来源:[J].The Journal of clinical endocrinology and metabolism, 2016, Vol.101 (5), pp.2201-10PubMed
摘要:The dynamic temporal relationship between changes in serum reproductive hormones and mortality in men has not been reported.;;The objective of the study was to examine the relationship between progressive changes in circulating reproductive hormones over time with all-cause and c...

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