PubMed期刊
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作者:Kokki Hannu
来源:[J].Pediatric Anesthesia, 2011PubMed
摘要:Every anesthetist should have the expertise to perform lumbar puncture that is the prerequisite to induce spinal anesthesia. Spinal anesthesia is easy and effective technique: small amount of local anesthetic injected in the lumbar cerebrospinal fluid provides highly effective an...
作者:Kokki Hannu , Kokki Merja
来源:[J].Clinical Drug Investigation(IF 1.915), 2010, Vol.30 (4), pp.251-8PubMed
摘要:Ketoprofen is a highly effective NSAID with antipyretic and analgesic properties for the symptomatic management of pain and fever in both adults and children.;;To compare three dose levels of ketoprofen with paracetamol (acetaminophen) in the management of fever in children.;;Two...
作者:Kokki Hannu , Kokki Merja
来源:[J].Clinical Drug Investigation(IF 1.915), 2010, Vol.30 (6), pp.375-86PubMed
摘要:Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children. To compare the efficacy and safety of ketoprofen with that of paracetamol (acetaminophen) and ibuprofen in the treatment of febrile conditions in children. Two pr...
作者:Kokki Hannu
来源:[J].Paediatric Drugs, 2010, Vol.12 (5), pp.313-29PubMed
摘要:The NSAID ketoprofen is used widely in the management of inflammatory and musculoskeletal conditions, pain, and fever in children and adults. Pharmacokinetic studies show that drug exposure after a single intravenous dose is similar in children and adults (after dose normalizatio...
作者:Kokki Hannu , Kumpulainen Elina ...
来源:[J].British Journal of Clinical Pharmacology, 2008, Vol.65 (6), pp.879-84PubMed
摘要:WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Diclofenac, a nonselective nonsteroidal anti-inflammatory drug,, exerts analgesic action both in the peripheral tissues and in the central nervous system by inhibiting cyclooxygenase enzymes COX-1/2, but central nervous system penetration...
作者:Kokki Hannu , Kumpulainen Elina ...
来源:[J].Pediatrics (English Edition), 2007, Vol.120 (4), pp.e1002-8PubMed
摘要:Ibuprofen is the most commonly used nonsteroidal, antipyretic, antiinflammatory analgesic in children. Nonsteroidal, antipyretic, antiinflammatory analgesics act in both the peripheral tissues and the central nervous system. The central nervous system penetration of ibuprofen has...
作者:Kokki Hannu , Rasanen Ilpo ...
来源:[J].Clinical Pharmacokinetics(IF 6.109), 2006, Vol.45 (7), pp.745-54PubMed
摘要:We evaluated and compared the pharmacokinetics of two oral administration routes of oxycodone parenteral liquid (10 mg/mL)--single buccal and sublingual administration--in 30 generally healthy awake children, aged 6-91 months.;;Two groups of children undergoing inpatient surgery ...
作者:Kokki Hannu , Laisalmi Merja , Vanamo Kari
来源:[J].Journal of Opioid Management, 2007, Vol.2 (5), pp.290-4PubMed
摘要:The results of studies exploring the efficacy of interpleural analgesia in children post-thoracotomy have frequently been inconclusive. In this pilot study, we have evaluated the efficacy and safety of interpleural bupivacaine and intravenous (IV) oxycodone in pain treatment afte...
作者:Kokki Hannu , Ylönen Paula ...
来源:[J].Anesthesia and Analgesia(IF 3.3), 2004, Vol.100 (1), pp.66-70PubMed
摘要:In this clinical trial, we evaluated the clinical effects of ropivacaine for spinal anesthesia in children. An open, prospective study was performed on 93 children, aged 1-17 yr, undergoing elective lower abdominal or lower limb surgery. A plain solution of ropivacaine 5 mg/mL at...
作者:Kokki Hannu , Lintula Hannu ...
来源:[J].Archives of Pediatrics & Adolescent Medicine(IF 4.282), 2005, Vol.159 (4), pp.320-5PubMed
摘要:Analgesics for children with acute abdominal pain are often withheld for fear that they might mask physical examination findings and thus might be unsafe. This viewpoint has been challenged recently.;;To evaluate the effects of buccal oxycodone on pain relief, physical examinatio...

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