PubMed期刊
期刊
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作者:Kim Jeffrey , Li Yong , Watkins Bruce A
来源:[J].Nutrition, 2011, Vol.27 (6), pp.624-32PubMed
摘要:The endocannabinoid (EC) signaling (ECS) system involves the activation of receptors targeted by endogenously produced ligands called endocannabinoids that trigger specific physiologic events in various organs and tissues throughout the body. ECs are lipid mediators that bin...
作者:Kim Jeffrey , Kimlin Lauren ...
来源:[J].Journal of Biological Chemistry(IF 4.651), 2009, Vol.284 (10), pp.6043-7PubMed
摘要:Oct4 is a known master regulator of stem cell renewal and differentiation. Expression of Oct4 during differentiation is regulated by promoter methylation by the nucleosome remodeling and histone deacetylation (NuRD) complex. Here, we show that Cdk2ap1, a negative regulator of Cdk...
作者:Kim Jeffrey , Greene Krista ...
来源:[J].The Journal of Neuropsychiatry and Clinical Neurosciences, 2009, Vol.21 (2), pp.216-9PubMed
摘要:Apathy has been observed in various types of neuropsychiatric illness, including degenerative, traumatic, and cerebrovascular. In this article, the authors describe the neurobiology of cerebrovascular induced apathy and its treatment.
作者:Kim Jeffrey , Moon Hyun-Seuk ...
来源:[J].Journal of Neurochemistry, 2009, Vol.111 (2), pp.510-21PubMed
摘要:Docosahexaenoic acid (DHA, 22:6n-3), the major polyunsaturated fatty acid accumulated in the brain during development, has been implicated in learning and memory, but underlying cellular mechanisms are not clearly understood. Here, we demonstrate that DHA significantly affects hi...
作者:Kim Jeffrey , Coble Dondrae J ...
来源:[J].Comparative medicine(IF 1.12), 2018, Vol.68 (2), pp.124-130PubMed
摘要:Antimicrobial resistance (AMR) presents serious threats to human and animal health. Although AMR of pathogens is often evaluated independently between humans and animals, comparative analysis of AMR between humans and animals is necessary for zoonotic pathogens. Major surveillanc...
作者:Kim Jeffrey , Coble Dondrae J ...
来源:[J].Comparative medicine(IF 1.12), 2019, Vol.68 (2), pp.124-130PubMed
摘要:Antimicrobial resistance (AMR) presents serious threats to human and animal health. Although AMR of pathogens is often evaluated independently between humans and animals, comparative analysis of AMR between humans and animals is necessary for zoonotic pathogens. Major surveillanc...
作者:Kim Jeffrey , Coble Dondrae J ...
来源:[J].Comparative medicine(IF 1.12), 2017, Vol.67 (1), pp.79-86PubMed
摘要:As a growing threat to human and animal health, antimicrobial resistance (AMR) has become a central public-health topic. Largescale surveillance systems, such as the National Antimicrobial Resistance Monitoring System (NARMS), are now established to monitor and provide guidance r...
作者:Kim Jeffrey , Abu Aboud Omran ...
来源:[J].Oncotarget(IF 6.636), 2016, Vol.7 (41), pp.66540-66557PubMed
摘要:Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing. Tryptophan metabolism, which produces immunosuppressive metabolites, is enhanc...
作者:Kim Jeffrey , Anderson Courtney M ...
来源:[J].Nature communications(IF 10.015), 2017, Vol.8 (1), pp.1998PubMed
摘要:Intra-tumor heterogeneity (ITH) is a major underlying cause of therapy resistance and disease recurrence, and is a read-out of tumor growth. Current genetic ITH analysis methods do not preserve spatial context and may not detect rare subclones. Here, we address these shortfalls b...
作者:Kim Jeffrey , Nuthikattu Saivageethi ...
来源:[J].Journal of lipid research, 2016, Vol.57 (6), pp.955-68PubMed
摘要:Dysfunction of the cerebrovasculature plays an important role in vascular cognitive impairment (VCI). Lipotoxic injury of the systemic endothelium in response to hydrolyzed triglyceride-rich lipoproteins (TGRLs; TGRL lipolysis products) or a high-fat Western diet (WD) suggests si...

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