国际光学工程学会
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作者:Junjie Yao , Jan Laufer
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (7), pp.070901-070901SPIE
摘要:Genetically encoded contrast in photoacoustic imaging (PAI) is complementary to the intrinsic contrast provided by endogenous absorbing chromophores such as hemoglobin. The use of reporter genes expressing absorbing proteins opens the possibility of visualizing dynamic cellular a...
作者:Junjie Yao , Lidai Wang ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2017, Vol.22 (4), pp.041002-041002SPIE
摘要:Optical-resolution photoacoustic microscopy (OR-PAM) offers label-free in vivo imaging with high spatial resolution by acoustically detecting optical absorption contrasts via the photoacoustic effect. We developed a compact handheld OR-PAM probe for fast photoacoustic imaging. Di...
作者:... Eric Tang , Jianwen Luo , Junjie Yao
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (1), pp.016014-016014SPIE
摘要:Temperature mapping during thermotherapy can help precisely control the heating process, both temporally and spatially, to efficiently kill the tumor cells and prevent the healthy tissues from heating damage. Photoacoustic tomography (PAT) has been used for noninvasive tempe...
作者:... Wei Liu , Jun Xia , Junjie Yao
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (3), pp.030506-030506SPIE
摘要:We report a photoacoustic computed tomography (PACT) system using a customized optical fiber with a cylindrical diffuser to internally illuminate deep targets. The traditional external light illumination in PACT usually limits the penetration depth to a few centimeters from the t...
作者:Junjie Yao , Terence T. W. Wong ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (7), pp.076001-076001SPIE
摘要:Optical-resolution photoacoustic microscopy (OR-PAM) has demonstrated fast, label-free volumetric imaging of optical-absorption contrast within the quasiballistic regime of photon scattering. However, the limited numerical aperture of the ultrasonic transducer restricts the detec...
作者:Junjie Yao , Rebecca C. Gilson ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (4), pp.046007-046007SPIE
摘要:We propose a calibration-free photoacoustic (PA) method for transverse flow measurements. In this method, a pulsed periodically structured (i.e., grating patterned) optical beam is used to illuminate flowing absorptive particles in an optically scattering medium. The PA signal am...
作者:Junjie Yao , Lei Li
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (6), pp.061002-061002SPIE
摘要:Myoglobin is an essential oxygen-binding hemoprotein in skeletal and cardiac muscles that buffers intracellular oxygen ( O 2 ) concentration in response to hypoxia or elevated muscle activities. We present a method that uses photoacoustic computed tomography to measure the distri...
作者:Junjie Yao , Konstantin I. Maslov
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (3), pp.037001-037001SPIE
摘要:Currently, laser fluence calibration is typically required for quantitative measurement of particle concentration in photoacoustic imaging. Here, we present a calibration-free method to quantify the absolute particle concentration by statistically analyzing photoacoustic signals....
作者:Yong Zhou , Junjie Yao , Lihong V. Wang
来源:[J].Journal of Biomedical Optics(IF 2.881), 2016, Vol.21 (6), pp.061007-061007SPIE
摘要:Photoacoustic tomography (PAT) has become one of the fastest growing fields in biomedical optics. Unlike pure optical imaging, such as confocal microscopy and two-photon microscopy, PAT employs acoustic detection to image optical absorption contrast with high-resolution deep...
作者:Junjie Yao , Chih-Hsien Huang ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (11), pp.116009-116009SPIE
摘要:Despite its critical function in coordinating the egress of inflammatory and immune cells out of tissues and maintaining fluid balance, the causative role of lymphatic network dysfunction in pathological settings is still understudied. Engineered-animal models and better noninvas...

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