Wiley期刊
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作者:Joseph R. Boyd , Rodrigo A. Grandy ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2016, Vol.231 (9), pp.2007-2013Wiley
摘要:Embryonic stem cells (ESCs) exhibit unrestricted and indefinite, but stringently controlled, proliferation, and can differentiate into any lineage in the body. In the current study, we test the hypothesis that expression of ribosomal RNA (rRNA) and ribosomal protein genes (R...
作者:Joseph R. Boyd , Jonathan A. R. Gordon ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2016, Vol.231 (11), pp.2474-2481Wiley
摘要:Alterations in the epigenetic landscape are fundamental drivers of aberrant gene expression that contribute to cancer progression and pathology. Understanding specific modes of epigenetic regulation can be used to identify novel biomarkers or targets for therapeutic interven...
作者:Joseph R. Boyd , Coralee E. Tye ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2), pp.1278-1290Wiley
摘要:Alterations in nuclear morphology are common in cancer progression. However, the degree to which gross morphological abnormalities translate into compromised higher‐order chromatin organization is poorly understood. To explore the functional links between gene expression and...
作者:Joseph R. Boyd , Andre J. van Wijnen ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (10), pp.6406-6413Wiley
摘要:Fidelity of histone gene regulation, and ultimately of histone protein biosynthesis, is obligatory for packaging of newly replicated DNA into chromatin. Control of histone gene expression within the 3‐dimensional context of nuclear organization is reflected by two well docum...

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