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作者:Joseph R. Boyd , Rodrigo A. Grandy ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2016, Vol.231 (9), pp.2007-2013Wiley
摘要:Embryonic stem cells (ESCs) exhibit unrestricted and indefinite, but stringently controlled, proliferation, and can differentiate into any lineage in the body. In the current study, we test the hypothesis that expression of ribosomal RNA (rRNA) and ribosomal protein genes (R...
作者:Joseph R. Boyd , Jonathan A. R. Gordon ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2016, Vol.231 (11), pp.2474-2481Wiley
摘要:Alterations in the epigenetic landscape are fundamental drivers of aberrant gene expression that contribute to cancer progression and pathology. Understanding specific modes of epigenetic regulation can be used to identify novel biomarkers or targets for therapeutic interven...

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