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作者:John Rojas , Cesar LondoÑo , Yhors Ciro
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2016, Vol.8 (3), pp.13-23IAS
摘要:In recent years, botanicals have gained importance due to their dermal photoprotective effect against the harmful UV radiation. This radiation generates reactive oxygen species which attack proteins, lipids, and nucleic acids among others. This leads to the cellular oxidation, wh...
作者:John Rojas , Yhors Ciro , Sandra Zapata
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2014, Vol.7 (1), pp.69-72IAS
摘要:Objective: The purpose of this work is to assess the ionotropic gelation of chitosan as a new method to encapsulate and increase the stability of ascorbic acid (AA).Methods: Chitosan was employed for the encapsulation of AA employing the technique of ionotropic gelation with...
作者:Edward Echeverri , John Rojas , Marcel Yepes
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2015, Vol.7 (11), pp.160-164IAS
摘要:Objective: To improve the tableting properties of sorbitol (SOR) via particle engineering through agglomeration with anhydrous calcium diphosphate (ACD) employing a house-made agglomerator.Methods: A novel SOR: ACD composites were produced by agglomeration at the 95:5; 80:20, 50:...
作者:Edwin Marin , John Rojas
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2015, Vol.7 (3), pp.242-248IAS
摘要:Objective: The purpose of this work is to cross link PVA with glutaraldehyde to develop new films with increased waterproof properties.Methods: Cross linking of PVA with glutaraldehyde was conducted at 70°C at a 1:10 and 1:5 PVA: glutaraldehyde ratios. pH and reaction times ...
作者:John Rojas , David Correa
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (10), pp.73-80IAS
摘要:Objective: To study microcrystalline cellulose II (MCCII) as new pelletization aid using the extrusion/spheronization technology.Methods: The effect of the spheronization rate and spheronization time was assessed by a response surface design. The shape descriptors and physical pr...
作者:John Rojas , David Correa
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (10), pp.182-186IAS
摘要:Objective: To study microcrystalline cellulose II (MCCII) as new pelletization aid for a high and low solubility drugs such as verapamil. HCl and carbamazepine, respectively.Methods: Approximately, 30 g of MCCII and drug mixtures were hydrated passed through a # 20 mesh sieved an...

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