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作者:Guanglei Zhang , Yuan Gao ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2018, Vol.23 (8), pp.085002-085002SPIE
摘要:Fluorescence molecular tomography (FMT) has been widely used in preclinical tumor imaging, which enables three-dimensional imaging of the distribution of fluorescent probes in small animal bodies via image reconstruction method. However, the reconstruction results are usually uns...
作者:Guanglei Zhang , Huangsheng Pu ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (5), pp.056012-056012SPIE
摘要:In conventional fluorescence molecular tomography, the distribution of fluorescent contrast agents is reconstructed with the assumption of constant concentration during data acquisition for each image frame. However, the concentration of fluorescent contrast target is usually tim...
作者:Guanglei Zhang , Jianwen Luo
来源:[J].Journal of Biomedical Optics(IF 2.881), 2014, Vol.19 (4), pp.046018-046018SPIE
摘要:Owing to the high degree of scattering of light through tissues, the ill-posedness of fluorescence molecular tomography (FMT) inverse problem causes relatively low spatial resolution in the reconstruction results. Unlike L2 regularization, L1 regularization can preserve the detai...
作者:Guanglei Zhang , Fei Liu ...
来源:[J].Journal of Biomedical Optics(IF 2.881), 2013, Vol.18 (4), pp.040505-040505SPIE
摘要:Pharmacokinetic rates have the potential to provide quantitative physiological and pathological information for biological studies and drug development. Fluorescence molecular tomography (FMT) is an attractive imaging tool for three-dimensionally resolving fluorophore distributio...

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