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作者:Gérald Simonneau , David Montani ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.53 (1)
摘要:Since the 1st World Symposium on Pulmonary Hypertension (WSPH) in 1973, pulmonary hypertension (PH) has been arbitrarily defined as mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest, measured by right heart catheterisation. Recent data from normal subjects has shown t...
作者:Gérald Simonneau , Marius M. Hoeper
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.49 (2)
摘要:Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare form of pulmonary hypertension, classified as group 4 in the present clinical classification [1, 2]. CTEPH is generally considered a late complication of one or multiple episodes of acute pulmonary embolism that have...
作者:Gérald Simonneau , Dominique Valeyre ...
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.50 (4)
摘要:Studies reporting the effects of modern strategies with pulmonary arterial hypertension (PAH)-targeted therapies in sarcoidosis-associated pulmonary hypertension (S-APH) are limited.(#br)Clinical and haemodynamic data from newly diagnosed patients with severe S-APH (mean pul...
作者:Gérald Simonneau , Eric Hachulla ...
来源:[J].European Respiratory Journal(IF 6.355), 2018, Vol.52 (4)
摘要:The prognostic importance of follow-up haemodynamics and the validity of multidimensional risk assessment are not well established for systemic sclerosis (SSc)-associated pulmonary arterial hypertension (PAH).(#br)We assessed incident SSc-PAH patients to determine the associ...
作者:Gérald Simonneau , Marc Humbert
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.50 (2)
摘要:Current European guidelines recommend periodic risk assessment for patients with pulmonary arterial hypertension (PAH). The aim of our study was to determine the association between the number of low-risk criteria achieved within 1 year of diagnosis and long-term prognosis.(...
作者:Gérald Simonneau , Florence Parent ...
来源:[J].European Respiratory Journal(IF 6.355), 2019, Vol.54 (6)
摘要:Rationale(#br)Precapillary pulmonary hypertension (PH) is a devastating complication of sickle cell disease (SCD). Little is known about the influence of the SCD genotype on PH characteristics.(#br)To describe clinical phenotypes and outcomes of precapillary PH due to SCD ac...
作者:Gérald Simonneau , Marc Humbert
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.50 (1)
摘要:This study aimed to describe the long-term outcomes of pulmonary arterial hypertension (PAH) induced by dasatinib.(#br)21 incident, right heart catheterisation-confirmed cases of dasatinib-induced PAH were identified from the French Pulmonary Hypertension Registry. Clinical ...
作者:Gérald Simonneau , Paul A. Corris ...
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.50 (3)
摘要:A proportion of pulmonary arterial hypertension (PAH) patients do not reach treatment goals with phosphodiesterase-5 inhibitors (PDE5i). RESPITE investigated the safety, feasibility and benefit of switching from PDE5i to riociguat in these patients.(#br)RESPITE was a 24-week...
作者:Gérald Simonneau , Olivier Sitbon ...
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.50 (2)
摘要:Patients with connective tissue disease-associated pulmonary arterial hypertension (PAH-CTD) have a poor prognosis compared with other aetiologies. The underlying CTD can influence treatment response and outcomes. We characterised the GRIPHON study PAH-CTD subgroup and evalu...
作者:Gérald Simonneau , Marc Humbert ...
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.50 (3)
摘要:Pulmonary hypertension (PH) is defined by resting mean pulmonary arterial pressure (mPAP) ≥25 mmHg [1]. Patients with pulmonary vascular disease (PVD) or left heart disease (LHD) may demonstrate abnormal haemodynamic responses to exercise even when resting mPAP is normal [2]...

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