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作者:John Rojas , David Correa
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (10), pp.73-80IAS
摘要:Objective: To study microcrystalline cellulose II (MCCII) as new pelletization aid using the extrusion/spheronization technology.Methods: The effect of the spheronization rate and spheronization time was assessed by a response surface design. The shape descriptors and physical pr...
作者:John Rojas , David Correa
来源:[J].International Journal of Pharmacy and Pharmaceutical Sciences, 2017, Vol.9 (10), pp.182-186IAS
摘要:Objective: To study microcrystalline cellulose II (MCCII) as new pelletization aid for a high and low solubility drugs such as verapamil. HCl and carbamazepine, respectively.Methods: Approximately, 30 g of MCCII and drug mixtures were hydrated passed through a # 20 mesh sieved an...

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