欧洲呼吸学会
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作者:Craig E. Wheelock , Stephen M. Rappaport
来源:[J].European Respiratory Journal(IF 6.355), 2020, Vol.55 (2)
摘要:Since the human genome was sequenced, extensive effort has been placed into mapping the role of genes in the onset of disease. It was expected that we would be able to explain the cause of disease and understand the genetic basis of health. However, we have found that while ...
作者:Craig E. Wheelock , Sven-Erik Dahlen ...
来源:[J].European Respiratory Journal(IF 6.355), 2020, Vol.55 (2)
摘要:Introduction(#br)Asthma is a heterogeneous condition, characterised by chronic inflammation of the airways, typically managed with inhaled bronchodilators and corticosteroids. In the case of uncontrolled asthma, oral corticosteroids (OCSs) are often prescribed. Good adherenc...
作者:... C. Magnus Sköld , Åsa M. Wheelock , Craig E. Wheelock
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.49 (6)
摘要:Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and a leading cause of mortality and morbidity worldwide. The aim of this study was to investigate the sex dependency of circulating metabolic profiles in COPD.(#br)Serum from healthy never-smokers (heal...
作者:... Ratko Djukanović , Timothy S.C. Hinks , Craig E. Wheelock
来源:[J].European Respiratory Journal(IF 6.355), 2017, Vol.49 (3)
摘要:In this study, we sought to determine whether asthma has a metabolic profile and whether this profile is related to disease severity.(#br)We characterised the serum from 22 healthy individuals and 54 asthmatics (12 mild, 20 moderate, 22 severe) using liquid chromatography–hi...
作者:Craig E. Wheelock , C. Magnus Sköld
来源:[J].European Respiratory Journal(IF 6.355), 2018, Vol.51 (5)
摘要:Chronic obstructive pulmonary disease (COPD) is an umbrella diagnosis caused by a multitude of underlying mechanisms, and molecular sub-phenotyping is needed to develop molecular diagnostic/prognostic tools and efficacious treatments.(#br)The objective of these studies was to inv...
作者:... C. Magnus Sköld , Åsa M. Wheelock , Craig E. Wheelock
来源:[J].European Respiratory Journal(IF 6.355), 2016, Vol.47 (6), pp.1645-1656
摘要:Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality; however, the role of inflammatory mediators in its pathobiology remains unclear. The aim of this study was to investigate the influence of gender in COPD on lipid mediator levels.(#br)Bronchoalveol...

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