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作者:Childress Paul J , Scofield David C ...
来源:[J].Comparative medicine(IF 1.12), 2018, Vol.68 (2), pp.131-138PubMed
摘要:Spaceflight results in bone loss like that associated with osteoporosis or decreased weight-bearing (for example, high-energy trauma such as explosive injuries and automobile accidents). Thus, the unique spaceflight laboratory on the International Space Station presents the oppor...
作者:Childress Paul J , Scofield David C ...
来源:[J].Comparative medicine(IF 1.12), 2019, Vol.68 (2), pp.131-138PubMed
摘要:Spaceflight results in bone loss like that associated with osteoporosis or decreased weight-bearing (for example, high-energy trauma such as explosive injuries and automobile accidents). Thus, the unique spaceflight laboratory on the International Space Station presents the oppor...
作者:Childress Paul J , Abeysekera Irushi ...
来源:[J].Blood advances, 2017, Vol.1 (26), pp.2520-2528PubMed
摘要:Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs) and their interaction with megakaryocytes to sustain HSC function ...
作者:Childress Paul J , Bidwell Joseph P ...
来源:[J].Endocrinology, 2011, Vol.152 (8), pp.2963-75PubMed
摘要:PTH is a potent calcium-regulating factor that has skeletal anabolic effects when administered intermittently or catabolic effects when maintained at consistently high levels. Bone cells express PTH receptors, but the cellular responses to PTH in bone are incompletely unders...
作者:Childress Paul J , Robling Alexander G ...
来源:[J].AJP: Endocrinology and Metabolism (Online), 2009, Vol.298 (3), pp.E714-25PubMed
摘要:Parathyroid hormone (PTH) restores bone mass to the osteopenic skeleton, but significant questions remain as to the underlying mechanisms. The receptor for advanced glycation end products (RAGE) is a multiligand receptor of the immunoglobulin superfamily; however, recent studies ...

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