Wiley期刊
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作者:Andrew J. Fritz , A. Rasim Barutcu ...
来源:[J].Journal of Cellular Biochemistry(IF 3.062), 2016, Vol.117 (1), pp.9-19Wiley
摘要:ABSTRACT(#br)The organization of interphase chromosomes in chromosome territories (CTs) was first proposed more than one hundred years ago. The introduction of increasingly sophisticated microscopic and molecular techniques, now provide complementary strategies for studying ...
作者:Andrew J. Fritz , Branislav Stojkovic ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2015, Vol.230 (2), pp.427-439Wiley
摘要:We present a 3‐D mapping in WI38 human diploid fibroblast cells of chromosome territories (CT) 13,14,15,21, and 22, which contain the nucleolar organizing regions (NOR) and participate in the formation of nucleoli. The nuclear radial positioning of NOR‐CT correlated with the...
作者:Andrew J. Fritz , Sayyed K. Zaidi ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2016, Vol.231 (1), pp.31-35Wiley
摘要:Three‐dimensional organization of the chromatin has important roles in transcription, replication, DNA repair, and pathologic events such as translocations. There are two fundamental ways to study higher‐order chromatin organization: microscopic and molecular approaches. In ...
作者:Andrew J. Fritz , Janet L. Stein ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2), pp.1291-1299Wiley
摘要:Long non‐coding RNAs (lncRNAs) are acknowledged as regulators of cancer biology and pathology. Our goal was to perform a stringent profiling of breast cancer cell lines that represent disease progression. We used the MCF‐10 series, which includes the normal‐like MCF‐10A...
作者:Andrew J. Fritz , Joseph R. Boyd ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (10), pp.6406-6413Wiley
摘要:Fidelity of histone gene regulation, and ultimately of histone protein biosynthesis, is obligatory for packaging of newly replicated DNA into chromatin. Control of histone gene expression within the 3‐dimensional context of nuclear organization is reflected by two well docum...
作者:Andrew J. Fritz , Sayyed K. Zaidi ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (12), pp.9136-9144Wiley
摘要:Breast cancer is the most common cancer in women, and accounts for ~30% of new cancer cases and 15% of cancer‐related deaths. Tumor relapse and metastasis are primary factors contributing to breast cancer‐related deaths. Therefore, the challenge for breast cancer treatment i...
作者:Andrew J. Fritz , Prachi N. Ghule ...
来源:[J].Journal of Cellular Physiology(IF 4.218), 2018, Vol.233 (2), pp.1278-1290Wiley
摘要:Alterations in nuclear morphology are common in cancer progression. However, the degree to which gross morphological abnormalities translate into compromised higher‐order chromatin organization is poorly understood. To explore the functional links between gene expression and...

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