European Cells and Materials (eCM)
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作者:L Germain , D Larouche , B Nedelec ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.128-141European Cells and Materials (eCM)
摘要:Split-thickness skin autografts (AGs) are the standard surgical treatment for severe burn injuries. However, the treatment of patients with substantial skin loss is limited by the availability of donor sites for skin harvesting. As an alternative to skin autografts, our rese...
作者:R Castro-Viñuelas , C Sanjurjo-Rodríguez , M Piñeiro-Ramil ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.96-109European Cells and Materials (eCM)
摘要:The establishment of cartilage regenerative medicine is an important clinical issue, but the search for cell sources able to restore cartilage integrity proves to be challenging. Human mesenchymal stromal cells (MSCs) are prone to form epiphyseal or hypertrophic cartilage and hav...
作者:J Antons , M G Marascio , P Aeberhard ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.81-95European Cells and Materials (eCM)
摘要:Tissue decellularisation has gained much attention in regenerative medicine as an alternative to synthetic materials. In decellularised tissues, biological cues can be maintained and provide cellular environments still unmet by synthetic materials. Supercritical CO 2 (scCO 2...
作者:T Onishi , T Shimizu , M Akahane ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.68-80European Cells and Materials (eCM)
摘要:The application of extracellular matrix (ECM) sheets without a scaffold is not extensively reported in bone regenerative medicine. The aim of the present study was to demonstrate that an osteogenic ECM sheet (OECMS) can retain ECM integrity and growth factors to enhance bone...
作者:J Melke , F Zhao , B van Rietbergen ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.57-68European Cells and Materials (eCM)
摘要:Spinner flask bioreactors have often been employed for bone tissue engineering. However, the reasons for their success in facilitating bone growth remain inconclusive. It was hypothesised that engineered bone tissue formation can be attributed to mechanical stimuli, which ca...
作者:R Bell , M A Robles-Harris , M Anderson ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.44-56European Cells and Materials (eCM)
摘要:Tendinopathy is a common and progressive musculoskeletal disease. Increased apoptosis is an end-stage tendinopathy manifestation, but its contribution to the pathology of the disease is unknown. A previously established in vivo model of fatigue damage accumulation shows that incr...
作者:A K Haudenschild , B E Sherlock , X Zhou ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.30-43European Cells and Materials (eCM)
摘要:Tissue engineers utilize a battery of expensive, time-consuming and destructive techniques to assess the composition and function of engineered tissues. A nondestructive solution to monitor tissue maturation would reduce costs and accelerate product development. As a first step t...
作者:M M Gao , Q N Su , T Z Liang ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.1-14European Cells and Materials (eCM)
摘要:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is the main source of extracellular pyrophosphate. Along with tissue-nonspecific alkaline phosphatase (TNAP), ENPP1 plays an important role in balancing bone mineralisation. Although well established in pre-osteoblasts, t...
作者:C L Yang , Y H Sun , W H Yu ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.15-29European Cells and Materials (eCM)
摘要:Pro-inflammatory phenotype (M1) macrophages initiate angiogenesis, while their prolonged activation can induce chronic inflammation. Anti-inflammatory phenotype (M2) macrophages promote vessel maturation and tissue regeneration. Biomaterials which can promote M2 polarisation...
作者:V Fischer , M Haffner-Luntzer , M Amling ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.365-385European Cells and Materials (eCM)
摘要:Calcium and vitamin D are essential for maintaining bone health. Therefore, deficiencies in calcium and vitamin D are major risk factors for osteoporosis development. Because sufficient amounts of calcium are also required for fracture-callus mineralisation, compromised bone repa...

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