European Cells and Materials (eCM)
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作者:T Onishi , T Shimizu , M Akahane ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.68-80European Cells and Materials (eCM)
摘要:The application of extracellular matrix (ECM) sheets without a scaffold is not extensively reported in bone regenerative medicine. The aim of the present study was to demonstrate that an osteogenic ECM sheet (OECMS) can retain ECM integrity and growth factors to enhance bone...
作者:J Melke , F Zhao , B van Rietbergen ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.57-68European Cells and Materials (eCM)
摘要:Spinner flask bioreactors have often been employed for bone tissue engineering. However, the reasons for their success in facilitating bone growth remain inconclusive. It was hypothesised that engineered bone tissue formation can be attributed to mechanical stimuli, which ca...
作者:R Bell , M A Robles-Harris , M Anderson ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.44-56European Cells and Materials (eCM)
摘要:Tendinopathy is a common and progressive musculoskeletal disease. Increased apoptosis is an end-stage tendinopathy manifestation, but its contribution to the pathology of the disease is unknown. A previously established in vivo model of fatigue damage accumulation shows that incr...
作者:A K Haudenschild , B E Sherlock , X Zhou ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.30-43European Cells and Materials (eCM)
摘要:Tissue engineers utilize a battery of expensive, time-consuming and destructive techniques to assess the composition and function of engineered tissues. A nondestructive solution to monitor tissue maturation would reduce costs and accelerate product development. As a first step t...
作者:M M Gao , Q N Su , T Z Liang ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.1-14European Cells and Materials (eCM)
摘要:Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) is the main source of extracellular pyrophosphate. Along with tissue-nonspecific alkaline phosphatase (TNAP), ENPP1 plays an important role in balancing bone mineralisation. Although well established in pre-osteoblasts, t...
作者:C L Yang , Y H Sun , W H Yu ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.15-29European Cells and Materials (eCM)
摘要:Pro-inflammatory phenotype (M1) macrophages initiate angiogenesis, while their prolonged activation can induce chronic inflammation. Anti-inflammatory phenotype (M2) macrophages promote vessel maturation and tissue regeneration. Biomaterials which can promote M2 polarisation...
作者:V Fischer , M Haffner-Luntzer , M Amling ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.365-385European Cells and Materials (eCM)
摘要:Calcium and vitamin D are essential for maintaining bone health. Therefore, deficiencies in calcium and vitamin D are major risk factors for osteoporosis development. Because sufficient amounts of calcium are also required for fracture-callus mineralisation, compromised bone repa...
作者:C S Chang , C Y Yang , H Y Hsiao ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.350-364European Cells and Materials (eCM)
摘要:Tissue engineering has the potential to overcome the limitations of tracheal reconstruction. To tissue-engineer a tracheal cartilage, auricular chondrocytes were encapsulated in a photocurable poly(ethylene glycol)/poly(ε-caprolactone) (PEG/PCL) hydrogel. Chondrogenic genes,...
作者:M Majewski , P Heisterbach , C Jaquiéry ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.318-334European Cells and Materials (eCM)
摘要:Several growth factors (GFs) are expressed as tendons heal, but it remains unknown whether their combined application enhances the healing process. This matter was addressed by applying a combination of basic fibroblast growth factor (bFGF), bone morphogenetic protein 12 (BM...
作者:D M Varma , H A Lin , R G Long ...
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.35, pp.300-317European Cells and Materials (eCM)
摘要:Back and neck pain are commonly associated with intervertebral disc (IVD) degeneration. Structural augmentation of diseased nucleus pulposus (NP) tissue with biomaterials could restore degeneration-related IVD height loss and degraded biomechanical behaviors; however, effective N...

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