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作者:Revathi Mannam , Indira Muzib Yallamalli
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (11), pp.106-109开放科学出版社
摘要:A new method for the quantitative determination of bosentan monohydrate in male rabbit plasma was developed by Reverse Phase HPLC as per standard regulatory guidelines. Precipitation method was used for extracting the drug from the drug spiked plasma using mobile phase. The ...
作者:Ahmed I. Khodair , Mostafa M. Elbadawi , Mohammed T. Elsaady ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (9), pp.58-68开放科学出版社
摘要:Novel 5-arylidene-3-(substituted phenyl)-2-(p-tolylamino)-3,5-dihydro-4H-imidazol-4-ones 9a-f were designed and synthesized based on a thioxoimidazolidinone derivative (I) that has been reported to have cytotoxicity with topoisomerase I inhibition. The synthesized compounds were ...
作者:Noohi Nasim , Jay Krishna Behera , I. Sriram Sandeep ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (10), pp.185-189开放科学出版社
摘要:Pandanus fascicularis L. commonly known as kewda is an important aromatic and medicinal plant belonging to the family Pandanaceae. The kewda oil has a characteristic aroma mainly due to the presence of phenyl ethyl methyl ether (PEME). In addition terpinen-4-ol, α-terpineol ...
作者:Tajudeen Olabisi Obafemi , Afolabi Clement Akinmoladun , Mary Tolulope Olaleye ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (11), pp.110-118开放科学出版社
摘要:This study was carried out to identify the phytochemicals present and in vitro antioxidant activity of methanol leaf extract of Synsepalum dulcificum (MSD). Standard protocols were used to evaluate the total phenols, total flavonoids and total antioxidants content of the ext...
作者:Laila H. Emara , Fatma M. Abdelfattah , Nesrin F. Taha
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (8), pp.156-167开放科学出版社
摘要:Low melting points Sucroesters (SEs) are used in hot-melt extrusion technology (HME). However, there are few literatures studying the effect of SEs on drug release and their storage stability. In this study, SE WE15 was proposed to prepare sustained-release solid dispersion...
作者:Ajit Anerao , Vikram Dighe , Satish John ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (10), pp.30-36开放科学出版社
摘要:Enantiomeric separation of Tedizolid phosphate was developed using a reversed phase HPLC (RP-HPLC) with &#𝛽;-cyclodextrin (&#𝛽;-CD) as a chiral mobile phase additive. Effect of the pH value of aqueous buffer, concentration of chiral additive, composition of mobile phase, a...
作者:Dalia O. Saleh , Sally A. El Awdan , Gehad A. Abdel Jaleel ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (8), pp.20-27开放科学出版社
摘要:Resveratrol (RSV) is a naturally occurring polyphenol recently postulated to be a powerful antioxidant, hepatoprotective and a potential anti-hyperglycemic. Our research aimed to investigate some possible mechanisms of action that may contribute to the efficacy of RSV to rev...
作者:Tri Dewanti Widyaningsih , Widya Dwi Rukmi Putri , Erni Sofia Murtini ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (7), pp.202-207开放科学出版社
摘要:Gout is a type of inflammatory arthritis that is triggered by the crystallization of uric acid. The therapeutic approach against gout is given by the treatment of inflammation and the control of hyperuricemia. This study aim to investigate whether glucosamine and chondroitin...
作者:D. Veera Nagendra Kumar , K. R. Shanmugam , Ch. Ramakrishna ...
来源:[J].Journal of Applied Pharmaceutical Science, 2017, Vol.7 (9), pp.76-80开放科学出版社
摘要:In this study, we observed hypoglycemic activity of Pimpinella tirupatinsis in STZ induced diabetic rats.In our study, we observed the modulation of mitochondrial enzymes by Pimpinella tirupatinsis in STZ induced diabetic rats.

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